Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6931772 | 0.87 | ALOX15 (0.41) | SMN1; SMN2ALDH1A1KDM4EALOX15RXFP1 | |
| SCHEMBL6931107 | 0.85 | ALOX15 (0.43) | SMN1; SMN2ALDH1A1KDM4EALOX15MAPT | |
| SCHEMBL10726439 | 0.72 | ALDH1A1 (0.46) | RAB9ANPC1SMN1; SMN2HSP90AA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10730472 | 0.71 | ALDH1A1 (0.45) | RAB9ANPC1SMN1; SMN2HSP90AA1ALDH1A1 | |
| SCHEMBL6270984 | 0.69 | HSP90AA1 (0.52) | RAB9ANPC1SMN1; SMN2HSP90AA1ALDH1A1 | |
| SCHEMBL11623381 | 0.67 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2HSP90AA1ALDH1A1 | |
| SCHEMBL25366081 | 0.64 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11539203 | 0.64 | MEN1 (0.66) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL11657490 | 0.64 | HSP90AA1 (0.50) | RAB9ANPC1SMN1; SMN2HSP90AA1ALDH1A1 | |
| SCHEMBL11627401 | 0.64 | SIGMAR1 (0.49) | RAB9ANPC1SMN1; SMN2HSP90AA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921803-A4 | METHODS FOR PREVENTING AND TREATING PESTIVIRUS INFECTION AND ASSOCIATED DISEASES | VIROPHARMA INC (US) | 2003-04-02 | — | — | EP | claimed |
| JP-2000501433-A | — | — | 2000-02-08 | — | — | JP | claimed |
| EP-0921803-A1 | METHODS FOR PREVENTING AND TREATING PESTIVIRUS INFECTION AND ASSOCIATED DISEASES | Viropharma Incorporated (US) | 1999-06-16 | — | — | EP | claimed |
| WO-1998036752-A1 | METHODS FOR PREVENTING AND TREATING PESTIVIRUS INFECTION AND ASSOCIATED DISEASES | VIROPHARMA INCORPORATED (US) | 1998-08-27 | — | — | WO | claimed |
| EP-0921803-A4 | METHODS FOR PREVENTING AND TREATING PESTIVIRUS INFECTION AND ASSOCIATED DISEASES | VIROPHARMA INC (US) | 2003-04-02 | — | — | EP | disclosed |
| EP-0921803-A1 | METHODS FOR PREVENTING AND TREATING PESTIVIRUS INFECTION AND ASSOCIATED DISEASES | Viropharma Incorporated (US) | 1999-06-16 | — | — | EP | disclosed |
| WO-1998036752-A1 | METHODS FOR PREVENTING AND TREATING PESTIVIRUS INFECTION AND ASSOCIATED DISEASES | VIROPHARMA INCORPORATED (US) | 1998-08-27 | — | — | WO | disclosed |