Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | PLAT | P00750 | 1/20 | 0.55 |
| ▸ | MME | P08473 | 2/20 | 0.55 |
| ▸ | ECE1 | P42892 | 2/20 | 0.55 |
| ▸ | CASP3 | P42574 | 2/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CTSD | P07339 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25287172 | 0.93 | ECE1 (0.61) | MMEECE1CASP3CASP7CTSD | |
| SCHEMBL3058668 | 0.93 | ECE1 (0.61) | MMEECE1CASP3CASP7CTSD | |
| SCHEMBL8588834 | 0.93 | ALDH1A1 (0.55) | F2PLAUPLATCASP3CASP7 | |
| SCHEMBL28252140 | 0.91 | ECE1 (0.64) | MMEECE1CASP3CASP7CTSD | |
| SCHEMBL8612642 | 0.91 | ECE1 (0.64) | MMEECE1CASP3CASP7CTSD | |
| SCHEMBL6271137 | 0.90 | CASP3 (0.64) | MMEECE1CASP3CASP7CTSD | |
| SCHEMBL8585984 | 0.89 | ECE1 (0.57) | MMEECE1CASP3CASP7CTSD | |
| SCHEMBL8492505 | 0.88 | MME (0.64) | MMEECE1ITGB3ITGA2BCTSD | |
| SCHEMBL8717685 | 0.87 | ITGB3 (0.66) | F2PLAUPLATMMEECE1 | |
| SCHEMBL7084689 | 0.87 | ITGB3 (0.66) | F2PLAUPLATMMEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998038990-A1 | METHOD OF TREATING TRAUMA ASSOCIATED WITH BRAIN, SPINAL CORD OR PERIPHERAL NERVE INJURY USING CARBOBENZYLOXY N-PROTECTED DI- AND TRIPEPTIDE PHENYLALANINALS | HOECHST MARION ROUSSEL, INC. (US) | 1998-09-11 | — | — | WO | disclosed |