Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | BID | P55957 | 3/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.32 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6273157 | 0.98 | LTB4R (0.39) | LTB4RLTB4R2PTGS2ALOX5PPARA | |
| SCHEMBL29173154 | 0.92 | PTGS2 (0.44) | LTB4RLTB4R2PTGS2ALOX5PPARA | |
| SCHEMBL4709952 | 0.90 | THRA (0.45) | LTB4RLTB4R2PTGS2ALOX5PPARA | |
| SCHEMBL3828938 | 0.90 | THRA (0.45) | LTB4RLTB4R2PTGS2ALOX5PPARA | |
| SCHEMBL11210213 | 0.89 | PTGS2 (0.44) | LTB4RLTB4R2PTGS2ALOX5PPARA | |
| SCHEMBL4712031 | 0.89 | LTB4R (0.43) | LTB4RLTB4R2PTGS2ALOX5PPARA | |
| SCHEMBL11138913 | 0.89 | LTB4R (0.43) | LTB4RLTB4R2PTGS2ALOX5PPARA | |
| SCHEMBL6272974 | 0.88 | THRA (0.45) | LTB4RLTB4R2PTGS2ALOX5PPARA | |
| SCHEMBL9008326 | 0.88 | THRA (0.45) | LTB4RLTB4R2PTGS2ALOX5PPARA | |
| SCHEMBL9326507 | 0.82 | LTB4R (0.45) | LTB4RLTB4R2PTGS2ALOX5PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005113665-A2 | PHENOL-FREE PHOSPHITES | DOVER CHEMICAL CORPORATION (US) | 2005-12-01 | — | — | WO | disclosed |