Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 4/20 | 0.36 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11138913 | 1.00 | LTB4R (0.43) | LTB4RLTB4R2PTGS2ALOX5PPARA | |
| SCHEMBL9294713 | 0.92 | LTB4R (0.48) | LTB4RLTB4R2PTGS2ALOX5PPARA | |
| SCHEMBL6271735 | 0.89 | LTB4R (0.39) | LTB4RLTB4R2PTGS2ALOX5PPARA | |
| SCHEMBL6273157 | 0.89 | LTB4R (0.39) | LTB4RLTB4R2PTGS2ALOX5PPARA | |
| SCHEMBL14686026 | 0.83 | PTGS2 (0.51) | LTB4RLTB4R2PTGS2ALOX5PPARA | |
| SCHEMBL5364072 | 0.82 | LTB4R (0.37) | LTB4RLTB4R2PTGS2ALOX5PPARA | |
| SCHEMBL78431 | 0.82 | LTB4R (0.37) | LTB4RLTB4R2PTGS2ALOX5PPARA | |
| SCHEMBL10348809 | 0.82 | PTGS2 (0.53) | LTB4RLTB4R2PTGS2ALOX5PPARA | |
| SCHEMBL28191406 | 0.81 | THRA (0.52) | LTB4RLTB4R2PTGS2ALOX5PPARA | |
| SCHEMBL8769634 | 0.81 | LTB4R (0.40) | LTB4RLTB4R2PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470735-B2 | Phenol-free phosphites | DOVER CHEMICAL CORPORATION (US) | 2008-12-30 | — | — | US | disclosed |
| WO-2005113665-A2 | PHENOL-FREE PHOSPHITES | DOVER CHEMICAL CORPORATION (US) | 2005-12-01 | — | — | WO | disclosed |
| US-20040180999-A1 | PHENOL-FREE PHOSPHITES | DOVER CHEMICAL CORPORATION (US) | 2004-09-16 | — | — | US | disclosed |