Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3552649 | 0.66 | LIMK2 (0.35) | GRIN2B | |
| SCHEMBL10373069 | 0.62 | RAB9A (0.46) | — | |
| SCHEMBL6803580 | 0.62 | GRIN2B (0.38) | GRIN2B | |
| SCHEMBL3827929 | 0.61 | ACHE (0.40) | — | |
| SCHEMBL27577360 | 0.61 | MCHR1 (0.42) | — | |
| SCHEMBL19438374 | 0.61 | F2RL3 (0.37) | F2RL3 | |
| SCHEMBL628000 | 0.60 | MAPT (0.42) | — | |
| SCHEMBL27547648 | 0.60 | HDAC1 (0.48) | — | |
| SCHEMBL21553790 | 0.58 | CHRM2 (0.44) | — | |
| SCHEMBL20702387 | 0.58 | TACR3 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |