Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4957323 | 0.80 | ACE (0.45) | MEN1HTTKMT2APIK3CAPIK3CD | |
| SCHEMBL4957308 | 0.80 | ACE (0.45) | MEN1HTTKMT2APIK3CAPIK3CD | |
| SCHEMBL5734401 | 0.80 | NPC1 (0.63) | MEN1HTTKMT2AMTORITGB3 | |
| Iodide SCHEMBL10827466 | 0.79 | NPC1 (0.62) | MEN1HTTKMT2AMTORITGB3 | |
| SCHEMBL4927632 | 0.77 | L3MBTL1 (0.53) | — | |
| SCHEMBL4927636 | 0.77 | L3MBTL1 (0.53) | — | |
| SCHEMBL6443274 | 0.77 | CASP3 (0.48) | NPC1RAB9A | |
| SCHEMBL1097863 | 0.76 | NPC1 (0.62) | HTTKMT2AMTORITGB3ITGB1 | |
| SCHEMBL5737098 | 0.76 | NPC1 (0.53) | MEN1KMT2APIK3CAMTORPIK3CD | |
| SCHEMBL5763695 | 0.75 | ITGB1 (0.79) | MEN1HTTKMT2APIK3CAPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005132746-A | PYRIDYLPYRROLIDINEDICARBOXAMIDE DERIVATIVE | TOKUYAMA CORP | 2005-05-26 | — | — | JP | disclosed |