Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | PREP | P48147 | 2/20 | 0.40 |
| ▸ | FAP | Q12884 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4957308 | 1.00 | ACE (0.45) | ACEMEN1HTTKMT2AERAP2 | |
| SCHEMBL6273381 | 0.80 | MEN1 (0.53) | MEN1HTTKMT2APIK3CAPIK3CD | |
| SCHEMBL8205698 | 0.79 | MEN1 (0.48) | ACEMEN1KMT2ALMNA | |
| SCHEMBL4957316 | 0.77 | MAPK10 (0.48) | MEN1HTTKMT2AHCRTR2DPP4 | |
| SCHEMBL26616469 | 0.77 | FKBP1A (0.45) | ACEERAP2ERAP1LNPEPDPP4 | |
| SCHEMBL26616464 | 0.77 | FKBP1A (0.45) | ACEERAP2ERAP1LNPEPDPP4 | |
| Trifluoroacetic Acid SCHEMBL9551619 | 0.76 | ACE (0.47) | ACEHTTERAP2ERAP1LNPEP | |
| SCHEMBL26616429 | 0.75 | PREP (0.67) | ACEDPP4PREPFAP | |
| SCHEMBL26616424 | 0.75 | PREP (0.67) | ACEDPP4PREPFAP | |
| SCHEMBL17345293 | 0.74 | PREP (0.69) | ACEDPP4PREPFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144230-B1 | GROWTH PROMOTANTS FOR ANIMALS | Pfizer Limited (GB) | 1990-08-08 | — | — | EP | claimed |
| EP-0144230-A2 | Growth promotants for animals | Pfizer Limited (GB) | 1985-06-12 | — | — | EP | claimed |
| US-7371721-B2 | Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes | SANOS BIOSCIENCE A/S (DK) | 2008-05-13 | — | — | US | disclosed |
| US-20050282749-A1 | Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes | SANOS BIOSCIENCE A/S | 2005-12-22 | — | — | US | disclosed |