Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.35 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6274051 | 1.00 | CYP1A2 (0.40) | CYP1A2CYP2C9CYP2C19ALDH1A1HPGD | |
| SCHEMBL18121289 | 0.77 | ALDH1A1 (0.46) | CYP1A2CYP2C9CYP2C19ALDH1A1HPGD | |
| SCHEMBL20345394 | 0.77 | ALDH1A1 (0.46) | CYP1A2CYP2C9CYP2C19ALDH1A1HPGD | |
| SCHEMBL20033568 | 0.77 | ALDH1A1 (0.46) | CYP1A2CYP2C9CYP2C19ALDH1A1HPGD | |
| SCHEMBL18091410 | 0.77 | ALDH1A1 (0.46) | CYP1A2CYP2C9CYP2C19ALDH1A1HPGD | |
| SCHEMBL11124037 | 0.75 | ALDH1A1 (0.50) | CYP1A2CYP2C9CYP2C19ALDH1A1HPGD | |
| SCHEMBL14296887 | 0.75 | ALDH1A1 (0.40) | CYP1A2CYP2C9CYP2C19ALDH1A1HPGD | |
| SCHEMBL3782873 | 0.74 | ALDH1A1 (0.43) | CYP1A2CYP2C9CYP2C19ALDH1A1HPGD | |
| SCHEMBL19843959 | 0.73 | ALDH1A1 (0.40) | CYP1A2CYP2C9CYP2C19ALDH1A1HPGD | |
| SCHEMBL17983228 | 0.73 | ALDH1A1 (0.52) | CYP1A2CYP2C9CYP2C19ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176752-A1 | Process for the preparation of piperidine derivatives | DELMAR CHEMICALS INC. (CA) | 2005-08-11 | — | — | US | disclosed |
| US-20050176752-A1 | Process for the preparation of piperidine derivatives | DELMAR CHEMICALS INC. (CA) | 2005-08-11 | — | — | US | disclosed |
| WO-2005066181-A1 | PROCESS FOR THE PREPARATION OF 1,3-DIOXOLO [4,5-C] PIPERIDIN-7-OLS AND RELATED COMPOUNDS | DELMAR CHEMICALS INC. (CA) | 2005-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176752-A1 | Process for the preparation of piperidine derivatives | HPD, AZI2, DHPS | CYP1A2 677/4885CYP2C9 802/4885CYP2C19 986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.