SCHEMBL6274158

SCHEMBL6274158

CCCCCCCCOC1CCC(C)(C)N(OC(=O)CCC(=O)O)C1(C)C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 10/20 0.35
PPARD Q03181 8/20 0.35
PPARA Q07869 8/20 0.35
LMNA P02545 2/20 0.35
MAPT P10636 2/20 0.35
HTT P42858 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
PLA2G1B P04054 1/20 0.35
MAPK1 P28482 1/20 0.35
RAD52 P43351 1/20 0.35
ATG4B Q9Y4P1 1/20 0.35
KDM4E B2RXH2 1/20 0.35
NAAA Q02083 1/20 0.33
PRKCA P17252 2/20 0.33
GPR84 Q9NQS5 7/20 0.33
HDAC11 Q96DB2 5/20 0.33
TSHR P16473 4/20 0.33
ALDH1A1 P00352 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2784563 0.95 LMNA (0.37) LMNAMAPTHTTNPSR1MEN1
SCHEMBL6269708 0.94 PPARG (0.39) PPARGPPARDPPARAMEN1KMT2A
SCHEMBL3668155 0.89 NAAA (0.36) PPARGPPARDPPARALMNAMAPT
SCHEMBL3629448 0.82 NAAA (0.39) PPARGPPARDPPARAMEN1KMT2A
SCHEMBL3632141 0.76 NAAA (0.43) PPARGPPARDPPARALMNAMAPT
SCHEMBL1937937 0.74 PPARG (0.40) PPARGPPARDPPARAMAPTMEN1
SCHEMBL23355261 0.73 GBA1 (0.38) LMNAMAPTHTTNPSR1MEN1
SCHEMBL194536 0.73 NAAA (0.47) LMNAMAPTNAAAPRKCA
SCHEMBL27459516 0.72 GBA1 (0.35) LMNAMAPTHTTNPSR1MEN1
Succinic Acid SCHEMBL27878762 0.70 GPR84 (0.42) PPARGPPARDPPARAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3145910-A1 PIPERIDINE-BASED STABILIZERS AND POLYMERS END-CAPPED WITH THE SAME Solvay Specialty Polymers USA, LLC. (US) 2017-03-29 EP disclosed
WO-2015176978-A1 PIPERIDINE-BASED STABILIZERS AND POLYMERS END-CAPPED WITH THE SAME SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2015-11-26 WO disclosed
WO-2005121234-A2 FLAME RETARDED POLYMER COMPOSITION WITH IMPROVED THERMAL STABILITY SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2005-12-22 WO disclosed