Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1C | P00326 | 2/20 | 0.38 |
| ▸ | ADH1A | P07327 | 2/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11535495 | 0.82 | ADH1C (0.42) | ADH1CADH1AADH1BTRPM8TSHR | |
| SCHEMBL11532323 | 0.74 | ADH1C (0.45) | ADH1CADH1AADH1BTRPM8TSHR | |
| SCHEMBL14855541 | 0.73 | ADH1C (0.40) | ADH1CADH1AADH1BTRPM8ALDH1A1 | |
| SCHEMBL14855543 | 0.73 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL27490903 | 0.72 | ADH1A (0.48) | ADH1CADH1AADH1BTRPM8TSHR | |
| SCHEMBL7786929 | 0.72 | ADH1C (0.44) | ADH1CADH1AADH1BTRPM8TSHR | |
| SCHEMBL9462834 | 0.71 | ADH1B (0.42) | ADH1CADH1AADH1BTRPM8TSHR | |
| SCHEMBL10453106 | 0.71 | ADH1B (0.42) | ADH1CADH1AADH1BTRPM8TSHR | |
| SCHEMBL7783983 | 0.70 | ADH1B (0.41) | ADH1CADH1AADH1BTRPM8TSHR | |
| SCHEMBL7560321 | 0.69 | TSHR (0.45) | ADH1CADH1AADH1BTRPM8TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040095-A1 | INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | ASTRAZENECA AB (SE) | 2005-05-06 | — | — | WO | disclosed |