Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.44 |
| ▸ | GSR | P00390 | 2/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4156931 | 1.00 | NOS2 (0.47) | NOS2NOS3NOS1SLC1A1GSR | |
| SCHEMBL4156927 | 1.00 | NOS2 (0.47) | NOS2NOS3NOS1SLC1A1GSR | |
| SCHEMBL29596215 | 0.89 | NOS3 (0.40) | NOS2NOS3NOS1SLC1A1GSR | |
| SCHEMBL17434420 | 0.85 | NOS3 (0.53) | NOS2NOS3NOS1SLC1A1GSR | |
| SCHEMBL9423322 | 0.85 | NOS3 (0.53) | NOS2NOS3NOS1SLC1A1GSR | |
| SCHEMBL8892097 | 0.85 | NOS3 (0.53) | NOS2NOS3NOS1SLC1A1GSR | |
| Hydrochloric Acid SCHEMBL8893490 | 0.82 | NOS3 (0.52) | NOS2NOS3NOS1SLC1A1GSR | |
| SCHEMBL12028657 | 0.82 | NOS2 (0.53) | NOS2NOS3NOS1SLC1A1GSR | |
| SCHEMBL13857278 | 0.82 | NOS2 (0.53) | NOS2NOS3NOS1SLC1A1GSR | |
| SCHEMBL17669888 | 0.79 | KIF11 (0.36) | NOS2NOS3NOS1SLC1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250296915-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2025-09-25 | — | — | US | claimed |
| US-20250296915-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2025-09-25 | — | — | US | disclosed |
| EP-2892565-A1 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DE) | 2015-07-15 | — | — | EP | disclosed |
| WO-2014037260-A1 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | DEUTSCHES ZENTRUM FÜR NEURODEGENERATIVE ERKRANKUNGEN E.V. (DE) | 2014-03-13 | — | — | WO | disclosed |
| EP-2705856-A1 | Compounds for the treatment of neurodegenerative disorders | Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DE) | 2014-03-12 | — | — | EP | disclosed |
| WO-2005087798-A1 | D-SER!8-CYCLOSPORINE MODIFIED ON THE HYDROXYL GROUP HAVING A SWITCHABLE INHIBITING EFFECT ON PROTEIN PHOSPHATASE CALCINEURINE AND SPECIFIC MANIPULIPULATABILITY OBTAINED THEREWITH OF THE IMMUNOSUPPRESSIVE EFFECT WHILE MAINTAINING INHIBITION OF PEPTIDYL-PROLYL-CIS-TRANS-ISOMERASE (PPI) E.G. FOR THE TREATMENT OF AUTOIMMUNE D | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2005-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250296915-A1 | NOVEL AMINO ACID DERIVATIVES | DNPEP, BCAT1, ANPEP | NOS2 2347/4885NOS3 2625/4885NOS1 2929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.