Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6274633 | 0.70 | RAB9A (0.76) | RAB9AMAPTNPC1SMN1; SMN2TP53 | |
| SCHEMBL11807554 | 0.65 | KDM4E (0.53) | RAB9AMAPTNPC1SMN1; SMN2TP53 | |
| SCHEMBL11807308 | 0.61 | RAB9A (0.50) | RAB9AMAPTNPC1SMN1; SMN2TP53 | |
| SCHEMBL855370 | 0.61 | RAB9A (1.00) | RAB9AMAPTNPC1SMN1; SMN2TP53 | |
| SCHEMBL8417801 | 0.61 | AURKA (0.44) | MAPTKMT2AALDH1A1MAOAMEN1 | |
| SCHEMBL30626329 | 0.60 | AURKA (0.45) | RAB9AMAPTNPC1SMN1; SMN2KMT2A | |
| SCHEMBL14939263 | 0.60 | RAB9A (0.57) | RAB9AMAPTNPC1SMN1; SMN2TP53 | |
| SCHEMBL14939531 | 0.60 | RAB9A (0.58) | RAB9AMAPTNPC1SMN1; SMN2TP53 | |
| SCHEMBL14939367 | 0.60 | MAPT (1.00) | RAB9AMAPTNPC1SMN1; SMN2TP53 | |
| SCHEMBL11813378 | 0.60 | RAB9A (0.49) | RAB9AMAPTNPC1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7148354-B2 | Process for preparation of donepezil | DR. REDDY'S LABORATORIES LIMITED (IN) | 2006-12-12 | — | — | US | disclosed |
| US-20040143121-A1 | Process for preparation of donepezil | DR. REDDY'S LABORATORIES LIMITED | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040143121-A1 | Process for preparation of donepezil | ACHE, ADH1C, COMT | RAB9A 3174/4885MAPT 200/4885NPC1 3452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.