Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8465610 | 0.98 | PDE4A (0.54) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL20855314 | 0.92 | PDE4A (0.50) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL1001815 | 0.82 | PDE4A (0.50) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL1656749 | 0.82 | PDE4A (0.50) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL6267186 | 0.82 | LMNA (0.62) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL3289378 | 0.81 | PDE4A (0.48) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL1005420 | 0.81 | PDE4A (0.59) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL4395512 | 0.81 | PDE4A (0.59) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL9355908 | 0.79 | PDE4A (0.57) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 | |
| SCHEMBL7994016 | 0.79 | PDE4A (0.57) | PDE4AUSP2SLCO1B1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8258210-B2 | Increasing compressive strength of cements without increasing setting time and polycarboxylic groups as dispersants | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2012-09-04 | — | — | US | disclosed |
| EP-1603846-B1 | STRENGTH IMPROVEMENT ADMIXTURE | CONSTR RES & TECH GMBH (DE) | 2012-07-11 | — | — | EP | disclosed |
| EP-1603846-A2 | STRENGTH IMPROVEMENT ADMIXTURE | Construction Research & Technology GmbH (DE) | 2005-12-14 | — | — | EP | disclosed |
| US-20040198873-A1 | Strength improvement admixture | CONSTRUCTION RESEARCH AND TECHNOLOGY GMBH | 2004-10-07 | — | — | US | disclosed |
| WO-2004076376-A2 | STRENGTH IMPROVEMENT ADMIXTURE | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2004-09-10 | — | — | WO | disclosed |