Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.31 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6712596 | 0.93 | GLA (0.37) | GLASMN1; SMN2CES2KDM4EMEN1 | |
| SCHEMBL41691 | 0.79 | ALDH1A1 (0.40) | GLASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL29242026 | 0.77 | MEN1 (0.37) | GLASMN1; SMN2CES2KDM4EMEN1 | |
| SCHEMBL3836552 | 0.74 | HK2 (0.44) | PLA2G7NPC1RAB9A | |
| SCHEMBL7776727 | 0.74 | SMN1; SMN2 (0.36) | GLASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL30659844 | 0.72 | ITGB3 (0.39) | ALDH1A1PLA2G7NPC1RAB9A | |
| SCHEMBL7310223 | 0.71 | TSHR (0.34) | ALDH1A1GAAPLA2G7 | |
| SCHEMBL15106032 | 0.70 | CES2 (0.38) | CES2ALDH1A1LMNA | |
| SCHEMBL6741817 | 0.70 | TRIM24 (0.43) | SMN1; SMN2KDM4EMEN1KMT2AMAPT | |
| Ethylene SCHEMBL7308236 | 0.69 | ITGB3 (0.37) | PLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606244-A2 | CYCLOALKYLAMIDES AND THEIR THERAPEUTIC USE AS ANTIEPILEPTIC AND ANTICONVULSANT | Abbott Laboratories (US) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004037769-A2 | CYCLOALKYLAMIDES AND THEIR THERAPEUTIC USE AS ANTIEPILEPTIC AND ANTICONVULSANT | ABBOTT LABORATORIES (US) | 2004-05-06 | — | — | WO | disclosed |