Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15180831 | 1.00 | POLB (0.44) | POLBLMNAKDM4EGAACYP2C19 | |
| SCHEMBL6276445 | 0.89 | PPIA (0.45) | POLBLMNAKDM4EGAAPPIA | |
| SCHEMBL31000747 | 0.89 | PPIA (0.45) | POLBLMNAKDM4EGAAPPIA | |
| SCHEMBL15209960 | 0.86 | CES2 (0.56) | POLBLMNAKDM4EGAAPPIA | |
| SCHEMBL180853 | 0.83 | ALDH1A1 (0.56) | POLBLMNAKDM4EGAAPPIA | |
| SCHEMBL29365220 | 0.83 | ALDH1A1 (0.56) | POLBLMNAKDM4EGAAPPIA | |
| SCHEMBL6913178 | 0.81 | ALDH1A1 (0.54) | POLBLMNAKDM4EGAAPPIA | |
| SCHEMBL6914996 | 0.81 | ALDH1A1 (0.54) | POLBLMNAKDM4EGAAPPIA | |
| SCHEMBL6913805 | 0.81 | ALDH1A1 (0.54) | POLBLMNAKDM4EGAAPPIA | |
| Hydrochloric Acid SCHEMBL8901291 | 0.81 | ALDH1A1 (0.54) | POLBLMNAKDM4EGAAPPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |
| US-20170296681-A1 | COMPOSITIONS AND METHODS FOR IMAGING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-10-19 | — | — | US | disclosed |
| US-20130209360-A1 | Compositions and Methods for Imaging | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-08-15 | — | — | US | disclosed |
| WO-2009020580-A1 | GAMMA SECRETASE MODULATORS | SCHERING CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170296681-A1 | COMPOSITIONS AND METHODS FOR IMAGING | GPX4, PRDX5, PRDX2 | POLB 1726/4885LMNA 1748/4885KDM4E 4684/4885 |
| US-20130209360-A1 | Compositions and Methods for Imaging | GPX4, PRDX5, PRDX2 | POLB 1726/4885LMNA 1748/4885KDM4E 4684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.