Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6281472 | 0.92 | ABCB1 (0.33) | ABCB1 | |
| SCHEMBL6277363 | 0.84 | CYP17A1 (0.31) | — | |
| SCHEMBL6274623 | 0.83 | — | — | |
| SCHEMBL6281046 | 0.83 | MAOB (0.33) | MAOBMPO | |
| SCHEMBL6281237 | 0.83 | ABCB1 (0.46) | MAOBABCB1HTR1ADRD2FLT1 | |
| SCHEMBL6281809 | 0.80 | ABCB1 (0.34) | ABCB1 | |
| SCHEMBL6277051 | 0.79 | ABCB1 (0.34) | ABCB1KDR | |
| SCHEMBL6274294 | 0.79 | MRGPRX4 (0.48) | MAOB | |
| SCHEMBL6274681 | 0.78 | NR3C2 (0.43) | MAOBNR3C2 | |
| SCHEMBL8409057 | 0.76 | HTR1A (0.37) | ABCB1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005116010-A1 | EP4 RECEPTOR AGONIST, COMPOSITIONS AND METHODS THEREOF | MERCK FROSST CANADA LTD. (CA) | 2005-12-08 | — | — | WO | claimed |