Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6390136 | 0.85 | ALDH1A1 (0.48) | MAPTLMNATP53NPC1RAB9A | |
| SCHEMBL6237563 | 0.70 | GSK3B (0.43) | — | |
| SCHEMBL6253146 | 0.69 | GSK3B (0.40) | MAPTLMNATP53NPC1RAB9A | |
| SCHEMBL6278086 | 0.69 | GSK3B (0.49) | MAPTLMNATP53NPC1RAB9A | |
| SCHEMBL8344591 | 0.67 | LMNA (0.74) | XDHMAPTLMNATP53NPC1 | |
| SCHEMBL20283668 | 0.65 | GAA (0.38) | MAPTLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4126308 | 0.65 | MAPT (0.50) | XDHMAPTLMNATP53NPC1 | |
| SCHEMBL19051717 | 0.65 | CYP17A1 (0.45) | XDHMAPTLMNATP53NPC1 | |
| Hydrochloric Acid SCHEMBL20265200 | 0.64 | GAA (0.37) | MAPTLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL12670786 | 0.63 | ALDH1A1 (0.44) | XDHMAPTLMNATP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551841-A1 | PYRAZOLOPYRIMIDINES AS KINASE INHIBITORS | SmithKline Beecham Corporation (US) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004009602-A1 | PYRAZOLOPYRIMIDINES AS KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-01-29 | — | — | WO | disclosed |