Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.74 |
| ▸ | MAPT | P10636 | 6/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.74 |
| ▸ | GAA | P10253 | 2/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | XDH | P47989 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 10/20 | 0.67 |
| ▸ | ALPL | P05186 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364028 | 0.85 | KDM4E (1.00) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL6206370 | 0.85 | KDM4E (0.73) | LMNAMAPTALDH1A1KDM4EGAA | |
| Hydrochloric Acid SCHEMBL6363785 | 0.84 | KDM4E (0.97) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL6071213 | 0.84 | KDM4E (0.76) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL6204720 | 0.84 | KDM4E (0.74) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL15214873 | 0.83 | TP53 (0.79) | LMNAMAPTALDH1A1KDM4EHTT | |
| SCHEMBL6071449 | 0.78 | KDM4E (0.75) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL8344398 | 0.78 | LMNA (0.67) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL6269930 | 0.78 | XDH (0.68) | LMNAMAPTALDH1A1KDM4EXDH | |
| SCHEMBL6203816 | 0.77 | MAPT (0.68) | LMNAMAPTALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004009602-A1 | PYRAZOLOPYRIMIDINES AS KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-01-29 | — | — | WO | disclosed |