Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6277493 | 0.87 | ADAMTS5 (0.42) | LMNASMN1; SMN2L3MBTL1NPC1PKM | |
| SCHEMBL6277028 | 0.80 | MMP9 (0.42) | LMNASMN1; SMN2L3MBTL1ALDH1A1ADAMTS5 | |
| SCHEMBL6277362 | 0.79 | ADAMTS5 (0.40) | LMNASMN1; SMN2L3MBTL1ALDH1A1ADAMTS5 | |
| SCHEMBL6302814 | 0.79 | ADAMTS5 (0.44) | LMNASMN1; SMN2L3MBTL1NPC1PKM | |
| SCHEMBL6276944 | 0.78 | ALDH1A1 (0.44) | LMNASMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL6276890 | 0.77 | ADAMTS5 (0.40) | LMNASMN1; SMN2L3MBTL1ALDH1A1ADAMTS5 | |
| SCHEMBL6278670 | 0.77 | ALOX5 (0.40) | LMNASMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL6270609 | 0.76 | ADAMTS5 (0.44) | LMNASMN1; SMN2L3MBTL1ALDH1A1ADAMTS5 | |
| SCHEMBL6277477 | 0.76 | ADAMTS5 (0.44) | LMNASMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL6271866 | 0.75 | ADAMTS5 (0.41) | LMNATRPM8SMN1; SMN2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092304-A2 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2005-10-06 | — | — | WO | disclosed |