Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MECP2 | P51608 | 3/20 | 0.47 |
| ▸ | MBD2 | Q9UBB5 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6274998 | 0.73 | RAB9A (0.67) | MAPTALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL2109517 | 0.64 | NR1H2 (0.43) | MAPTALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL744730 | 0.62 | L3MBTL1 (0.62) | MAPTALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL22001702 | 0.62 | RAB9A (0.51) | MAPTALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL2047875 | 0.61 | TP53 (0.55) | MAPTALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL1045908 | 0.60 | TNKS (0.46) | MAPTALDH1A1RAB9AKDM4EHPGD | |
| Guaiacol SCHEMBL28849222 | 0.59 | TP53 (0.72) | MAPTALDH1A1RAB9AKDM4EGAA | |
| SCHEMBL5480007 | 0.59 | ABCB1 (0.53) | MAPTALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL4425113 | 0.59 | SYK (0.56) | MAPTALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL24715480 | 0.58 | LMNA (0.50) | MAPTALDH1A1NPC1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092304-A2 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2005-10-06 | — | — | WO | claimed |
| WO-2005092304-A2 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2005-10-06 | — | — | WO | disclosed |