Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1269478 | 0.84 | RAB9A (0.42) | SMN1; SMN2RAB9AALDH1A1ALOX12TSHR | |
| SCHEMBL871729 | 0.82 | ALDH1A1 (0.44) | SMN1; SMN2RAB9AALDH1A1ALOX12TSHR | |
| SCHEMBL10015377 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9AALDH1A1ALOX12TSHR | |
| SCHEMBL9614885 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9AALDH1A1ALOX12TSHR | |
| SCHEMBL10673205 | 0.78 | ALDH1A1 (0.40) | SMN1; SMN2RAB9AALDH1A1ALOX12TSHR | |
| SCHEMBL16405303 | 0.78 | RAB9A (0.40) | SMN1; SMN2RAB9AALDH1A1ALOX12TSHR | |
| SCHEMBL11007672 | 0.77 | LMNA (0.42) | SMN1; SMN2RAB9AALDH1A1TSHRLMNA | |
| SCHEMBL31440989 | 0.77 | SLC22A6 (0.42) | SMN1; SMN2RAB9AALDH1A1ALOX12TSHR | |
| SCHEMBL19760179 | 0.76 | GAA (0.42) | SMN1; SMN2RAB9AALDH1A1ALOX12TSHR | |
| SCHEMBL18825259 | 0.73 | FAAH (0.40) | SMN1; SMN2RAB9AALDH1A1ALOX12TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941738-B1 | Antigenic conjugates of conserved lipooligosaccharides of gram negative bacteria | WYETH CORP (US) | 2005-05-11 | — | — | EP | claimed |
| EP-0382781-B1 | COMPOSITION FOR TREATING CANCERS CHARACTERIZED BY OVER-EXPRESSION OF THE C-FMS PROTO-ONCOGENE | GENETICS INSTITUTE, INC. (US) | 1993-09-29 | — | — | EP | claimed |
| EP-0863401-B1 | Analytical test device with liquid-filled blister | ROCHE DIAGNOSTICS GMBH (DE) | 2002-08-28 | — | — | EP | disclosed |
| US-6159747-A | Analytical test element with a blister filled with liquid | ROCHE DIAGNOSTICS GMBH (DE) | 2000-12-12 | — | — | US | disclosed |
| EP-0650054-B1 | Process and device for obtaining and detecting immunologically reactive substances from the gas phase | SECURETEC GMBH (DE) | 2000-08-30 | — | — | EP | disclosed |
| EP-0863401-A1 | Analytical test device with liquid-filled blister | Roche Diagnostics GmbH (DE) | 1998-09-09 | — | — | EP | disclosed |
| EP-0478715-B1 | TARGETED LIPOSOMES AND METHODS FOR LIPOSOME-PROTEIN COUPLING | LIPOSOME CO INC (US) | 1996-04-03 | — | — | EP | disclosed |
| US-5419914-A | Drug delivery | VESTAR, INC. (US) | 1995-05-30 | — | — | US | disclosed |
| EP-0650054-A2 | Process and device for obtaining and detecting immunologically reactive substances from the gas phase | Roche Diagnostics GmbH (DE) | 1995-04-26 | — | — | EP | disclosed |
| US-5399331-A | Drug delivery, medical diagnosis | THE LIPOSOME COMPANY, INC. (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0555317-B1 | PHOSPHOLIPID ANALOGUE VESICLE WITH A SUCCINIMIDYL MOIETY | VESTAR INC (US) | 1995-03-15 | — | — | EP | disclosed |
| EP-0555317-A1 | PHOSPHOLIPID ANALOGUE VESICLE WITH A SUCCINIMIDYL MOIETY. | VESTAR INC (US) | 1993-08-18 | — | — | EP | disclosed |
| WO-1992005773-A1 | PHOSPHOLIPID ANALOGUE VESICLE WITH A SUCCINIMIDYL MOIETY | VESTAR, INC. (US) | 1992-04-16 | — | — | WO | disclosed |
| WO-1991000289-A2 | TARGETED LIPOSOMES AND METHODS FOR LIPOSOME-PROTEIN COUPLING | THE LIPOSOME COMPANY, INC. (US) | 1991-01-10 | — | — | WO | disclosed |