Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | POLR1A | O95602 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1402380 | 0.76 | RAB9A (0.76) | KDM4EALDH1A1LMNACREBBPKMT2A | |
| SCHEMBL6264342 | 0.75 | HPGD (0.49) | KDM4EALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL1362247 | 0.71 | KDM4E (0.50) | KDM4EALDH1A1LMNACREBBPKMT2A | |
| SCHEMBL14817956 | 0.71 | KMT2A (0.76) | KDM4EALDH1A1LMNACREBBPKMT2A | |
| SCHEMBL17428293 | 0.70 | KMT2A (0.58) | KDM4EALDH1A1LMNACREBBPKMT2A | |
| SCHEMBL6157584 | 0.70 | KCNA5 (0.43) | KMT2ARAB9APOLBMEN1 | |
| SCHEMBL28623961 | 0.70 | CREBBP (1.00) | KDM4EALDH1A1LMNACREBBPKMT2A | |
| SCHEMBL20016690 | 0.69 | KMT2A (0.57) | KDM4EALDH1A1LMNACREBBPKMT2A | |
| SCHEMBL20852069 | 0.69 | KDM4E (0.58) | KDM4EALDH1A1LMNACREBBPKMT2A | |
| SCHEMBL12177839 | 0.69 | RAB9A (0.61) | KDM4EALDH1A1LMNACREBBPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597245-A1 | BENZOTHIAZEPINE AND BENZOTHIEPINE DERIVATIVES | AstraZeneca AB (SE) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004076430-A1 | BENZOTHIAZEPINE AND BENZOTHIEPINE DERIVATIVES | ASTRAZENECA AB (SE) | 2004-09-10 | — | — | WO | disclosed |