Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.51 |
| ▸ | RXRB | P28702 | 2/20 | 0.51 |
| ▸ | RXRG | P48443 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CFD | P00746 | 2/20 | 0.47 |
| ▸ | F11 | P03951 | 2/20 | 0.47 |
| ▸ | TPSB2 | P20231 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25913045 | 0.87 | L3MBTL1 (0.49) | RXRARXRBRXRGL3MBTL1LMNA | |
| SCHEMBL11839396 | 0.85 | CFD (0.47) | CFDF11TPSB2PLGPLAU | |
| SCHEMBL5036095 | 0.84 | NR1H4 (0.52) | CFDF11TPSB2PLGPLAU | |
| SCHEMBL1628791 | 0.80 | L3MBTL1 (0.62) | L3MBTL1GLACFDF11TPSB2 | |
| SCHEMBL21939140 | 0.80 | SRC (0.53) | RXRARXRBRXRGL3MBTL1GLA | |
| SCHEMBL28063443 | 0.80 | KDM4E (0.51) | RXRARXRBL3MBTL1LMNAHDAC1 | |
| Hydrochloric Acid SCHEMBL2525349 | 0.79 | L3MBTL1 (0.61) | L3MBTL1GLACFDF11TPSB2 | |
| SCHEMBL21900449 | 0.78 | CHRM1 (0.51) | L3MBTL1GLAGAATSHRCAMK2A | |
| SCHEMBL6498950 | 0.78 | ADRB3 (0.60) | RXRARXRBL3MBTL1GLALMNA | |
| SCHEMBL29844957 | 0.78 | THRB (0.47) | RXRARXRBRXRGL3MBTL1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092062-A2 | COMPOUNDS FOR NEURODEGENERATIVE DISORDERS | MYRIAD GENETICS, INC. (US) | 2005-10-06 | — | — | WO | disclosed |