Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | MECP2 | P51608 | 1/20 | 0.31 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6277126 | 0.88 | ALDH1A1 (0.45) | ADAMTS5KDM4EMAPTALDH1A1NPC1 | |
| SCHEMBL6266369 | 0.87 | ADAMTS5 (0.39) | ADAMTS5KDM4EMAPTALDH1A1NPC1 | |
| SCHEMBL6277544 | 0.85 | KDM4E (0.34) | KDM4EMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL6262688 | 0.80 | KMT2A (0.36) | KDM4EMAPTALDH1A1NPC1HPGD | |
| SCHEMBL6278050 | 0.79 | SIRT1 (0.38) | ADAMTS5KDM4EMAPTALDH1A1NPC1 | |
| SCHEMBL6274201 | 0.78 | ADAMTS5 (0.37) | ADAMTS5KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL6260436 | 0.74 | MECP2 (0.47) | ADAMTS5KDM4EMAPTALDH1A1NPC1 | |
| SCHEMBL6260546 | 0.74 | ADAMTS5 (0.36) | ADAMTS5KDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6271657 | 0.73 | KDM4E (0.44) | ADAMTS5KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL6268735 | 0.73 | GCGR (0.39) | ADAMTS5KDM4EMAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092304-A2 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2005-10-06 | — | — | WO | claimed |