Cinnamic Acid

Cinnamic Acid

SCHEMBL6278328

O=C(O)/C=C/c1ccccc1.c1ccc2ncccc2c1

nearest known ligand 0.63

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.63
HDAC3 O15379 1/20 0.61
TNKS O95271 1/20 0.61
HDAC4 P56524 1/20 0.61
HDAC1 Q13547 1/20 0.61
HCAR2 Q8TDS4 1/20 0.61
HDAC7 Q8WUI4 1/20 0.61
HDAC2 Q92769 1/20 0.61
HDAC10 Q969S8 1/20 0.61
HDAC11 Q96DB2 1/20 0.61
HDAC8 Q9BY41 1/20 0.61
TNKS2 Q9H2K2 1/20 0.61
HDAC6 Q9UBN7 1/20 0.61
HDAC9 Q9UKV0 1/20 0.61
HDAC5 Q9UQL6 1/20 0.61
CYP3A4 P08684 3/20 0.56
LMNA P02545 4/20 0.55
KDM4E B2RXH2 2/20 0.55
ALDH1A1 P00352 2/20 0.55
MAPT P10636 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cinnamic Acid SCHEMBL6278329 1.00 RAB9A (0.63) RAB9AHDAC3TNKSHDAC4HDAC1
Quinoline SCHEMBL7884120 0.88 ALDH1A1 (0.65) RAB9ACYP3A4LMNAKDM4EALDH1A1
Quinoline SCHEMBL5874264 0.88 ALDH1A1 (0.65) RAB9ACYP3A4LMNAKDM4EALDH1A1
Quinoline SCHEMBL27800002 0.88 ALDH1A1 (0.65) RAB9ACYP3A4LMNAKDM4EALDH1A1
Quinoline SCHEMBL5874841 0.88 ALDH1A1 (0.65) RAB9ACYP3A4LMNAKDM4EALDH1A1
Quinoline SCHEMBL5874253 0.88 ALDH1A1 (0.65) RAB9ACYP3A4LMNAKDM4EALDH1A1
Quinoline SCHEMBL7886403 0.88 ALDH1A1 (0.65) RAB9ACYP3A4LMNAKDM4EALDH1A1
Quinoline SCHEMBL5874270 0.88 ALDH1A1 (0.65) RAB9ACYP3A4LMNAKDM4EALDH1A1
Quinoline SCHEMBL7886400 0.88 ALDH1A1 (0.65) RAB9ACYP3A4LMNAKDM4EALDH1A1
Quinoline SCHEMBL27293512 0.88 ALDH1A1 (0.65) RAB9ACYP3A4LMNAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1580227-A1 Polymer additive composition for a host polymer and methods for making such composition NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2005-09-28 EP disclosed
WO-2005087856-A1 POLYMER ADDITIVE COMPOSITION FOR A HOST POLYMER AND METHODS FOR MAKING SUCH COMPOSITION NEDERLANDSE ORGANISATIE VOOR TOEGEPAST- NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2005-09-22 WO disclosed