SCHEMBL6280149

SCHEMBL6280149

Cc1cc(OC/C=C/C(F)(F)F)nc(Oc2csc(C(F)(F)F)c2)c1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6280151 1.00 POLB (0.30) POLBATM
SCHEMBL6612446 0.87
SCHEMBL6612441 0.87
SCHEMBL8121568 0.84 LMNA (0.34) POLBATM
SCHEMBL6608707 0.80
SCHEMBL6608703 0.80
SCHEMBL8127025 0.79 LMNA (0.39) POLBATM
SCHEMBL8309762 0.78 SYK (0.35)
SCHEMBL8127225 0.78 NUDT1 (0.38)
SCHEMBL6281931 0.78 MAPK1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020198381-A1 Herbicidal pyridine compounds INTELLECTUAL PROPERTY DEPARTMENT BASF AKTIENGESELLSCHAFT (DE) 2002-12-26 US claimed
US-6420315-B1 5-THIEN-3-YL-2-OXY- OR -2-THIO-PYRIDINES; HIGH SELECTIVITY FOR BROADLEAF AND GRASSY WEEDS IN CROPS, SUCH AS MAIZE AND RICE; PRE- AND POST-EMERGENCE BASF AKTIENGESELLSCHAFT (DE) 2002-07-16 US claimed
EP-0955300-A2 Herbicidal pyridine compounds American Cyanamid Company (US) 1999-11-10 EP claimed
US-6852673-B2 Herbicidal pyridine compounds BASF AKTIENGESELLSCHAFT (DE) 2005-02-08 US disclosed
US-20020198381-A1 Herbicidal pyridine compounds INTELLECTUAL PROPERTY DEPARTMENT BASF AKTIENGESELLSCHAFT (DE) 2002-12-26 US disclosed
US-6420315-B1 5-THIEN-3-YL-2-OXY- OR -2-THIO-PYRIDINES; HIGH SELECTIVITY FOR BROADLEAF AND GRASSY WEEDS IN CROPS, SUCH AS MAIZE AND RICE; PRE- AND POST-EMERGENCE BASF AKTIENGESELLSCHAFT (DE) 2002-07-16 US disclosed
US-6130188-A Herbicidal pyridine compounds AMERICAN CYANAMID COMPANY (US) 2000-10-10 US disclosed
EP-0955300-A2 Herbicidal pyridine compounds American Cyanamid Company (US) 1999-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020198381-A1 Herbicidal pyridine compounds HAX1, CYP4X1, PRDX1 POLB 4071/4885ATM 3016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.