Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | AMPD2 | Q01433 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6280917 | 0.90 | AMPD2 (0.37) | GAAELANEKDM4EALDH1A1AMPD2 | |
| SCHEMBL6281799 | 0.90 | TDP1 (0.45) | POLBKDM4EALDH1A1AMPD2SMN1; SMN2 | |
| SCHEMBL7489542 | 0.66 | GAA (0.38) | GAAPOLBELANEKDM4EALDH1A1 | |
| SCHEMBL2005895 | 0.62 | CA12 (0.54) | KDM4ECA12CA9 | |
| SCHEMBL5519932 | 0.62 | GAA (0.41) | GAAELANEKDM4EALDH1A1AMPD2 | |
| SCHEMBL6548965 | 0.61 | GAA (0.47) | GAAELANEALDH1A1AMPD2CA12 | |
| SCHEMBL26981274 | 0.60 | ELANE (0.50) | GAAELANEKDM4EALDH1A1CTSG | |
| SCHEMBL7449986 | 0.60 | ELANE (0.50) | GAAELANEALDH1A1AMPD2CTSG | |
| SCHEMBL11694722 | 0.59 | GAA (0.45) | GAAELANEALDH1A1AMPD2CTSG | |
| SCHEMBL13985003 | 0.58 | GAA (0.47) | GAAPOLBELANEHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1308316-C | Alpha-phenyl-beta-ketosulfone | BAYER AG (DE) | 2007-04-04 | — | — | CN | disclosed |
| US-6849744-B2 | α-phenyl-β-keto sulfones | BAYER AKTIENGESELLSCHAFT (DE) | 2005-02-01 | — | — | US | disclosed |
| US-20040063669-A1 | Alpha-phenyl-beta-ketosulfone | FISCHER REINER (DE) | 2004-04-01 | — | — | US | disclosed |
| US-6670385-B1 | Fungicides, herbicides and insecticides for crops | BAYER AKTIENGESELLSCHAFT (DE) | 2003-12-30 | — | — | US | disclosed |
| CN-1364162-A | Alpha-phenyl-beta-ketosulfone | BAYER AG (DE) | 2002-08-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063669-A1 | Alpha-phenyl-beta-ketosulfone | CYP2S1, SULT1E1, SKP1 | GAA 739/4885POLB 1554/4885ELANE 4102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.