Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMPD2 | Q01433 | 3/20 | 0.37 |
| ▸ | DHFR | P00374 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6280333 | 0.90 | GAA (0.39) | AMPD2CA12CA9ALDH1A1SMN1; SMN2 | |
| SCHEMBL5001010 | 0.69 | CACNA1G (0.38) | ALDH1A1KMT2ADRD2SIGMAR1 | |
| SCHEMBL2357828 | 0.61 | NR1H3 (0.55) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL12206274 | 0.59 | NR1H3 (0.56) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL18931674 | 0.58 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL7489542 | 0.58 | GAA (0.38) | ALDH1A1SMN1; SMN2MEN1KMT2AELANE | |
| SCHEMBL5435554 | 0.58 | PTGDR2 (0.54) | ALDH1A1 | |
| SCHEMBL28824747 | 0.58 | CHRM2 (0.41) | AMPD2MEN1KMT2ADRD2HTR7 | |
| SCHEMBL5519932 | 0.58 | GAA (0.41) | AMPD2ALDH1A1MEN1KMT2ASIGMAR1 | |
| SCHEMBL6548965 | 0.57 | GAA (0.47) | AMPD2CA12CA9ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849744-B2 | α-phenyl-β-keto sulfones | BAYER AKTIENGESELLSCHAFT (DE) | 2005-02-01 | — | — | US | disclosed |
| US-20040063669-A1 | Alpha-phenyl-beta-ketosulfone | FISCHER REINER (DE) | 2004-04-01 | — | — | US | disclosed |
| US-6670385-B1 | Fungicides, herbicides and insecticides for crops | BAYER AKTIENGESELLSCHAFT (DE) | 2003-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063669-A1 | Alpha-phenyl-beta-ketosulfone | CYP2S1, SULT1E1, SKP1 | AMPD2 4527/4885DHFR 796/4885CA12 4714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.