Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.38 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6280333 | 0.90 | GAA (0.39) | AMPD2ALDH1A1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL6280917 | 0.81 | AMPD2 (0.37) | SIGMAR1AMPD2LMNAALDH1A1KDM4E | |
| SCHEMBL28080831 | 0.64 | NR1H2 (0.58) | TDP1SIGMAR1MAPTLMNAALDH1A1 | |
| SCHEMBL7513351 | 0.62 | MAPT (0.46) | TDP1SIGMAR1AMPD2MAPTLMNA | |
| SCHEMBL28550434 | 0.62 | AR (0.56) | MAPTLMNAALDH1A1KDM4EMAPK1 | |
| SCHEMBL5437022 | 0.61 | MKNK1 (0.62) | SIGMAR1LMNAALDH1A1PPARG | |
| SCHEMBL11614006 | 0.60 | KMT2A (0.51) | TDP1SIGMAR1MAPTLMNATP53 | |
| SCHEMBL3186423 | 0.60 | SMN1; SMN2 (0.56) | TDP1SIGMAR1MAPTLMNATP53 | |
| SCHEMBL7489542 | 0.59 | GAA (0.38) | LMNAALDH1A1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL11811596 | 0.59 | SIGMAR1 (0.50) | TDP1SIGMAR1AMPD2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1308316-C | Alpha-phenyl-beta-ketosulfone | BAYER AG (DE) | 2007-04-04 | — | — | CN | disclosed |
| US-6849744-B2 | α-phenyl-β-keto sulfones | BAYER AKTIENGESELLSCHAFT (DE) | 2005-02-01 | — | — | US | disclosed |
| US-20040063669-A1 | Alpha-phenyl-beta-ketosulfone | FISCHER REINER (DE) | 2004-04-01 | — | — | US | disclosed |
| US-6670385-B1 | Fungicides, herbicides and insecticides for crops | BAYER AKTIENGESELLSCHAFT (DE) | 2003-12-30 | — | — | US | disclosed |
| CN-1364162-A | Alpha-phenyl-beta-ketosulfone | BAYER AG (DE) | 2002-08-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063669-A1 | Alpha-phenyl-beta-ketosulfone | CYP2S1, SULT1E1, SKP1 | TDP1 1808/4885SIGMAR1 471/4885AMPD2 4527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.