Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | FPR1 | P21462 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6287411 | 0.78 | MEN1 (0.42) | ALDH1A1TDP1KMT2AMAPTMEN1 | |
| SCHEMBL6284400 | 0.77 | KDM4E (0.45) | ALDH1A1KDM4EMAPTACHEHTT | |
| SCHEMBL6284373 | 0.75 | KMT2A (0.48) | ALDH1A1KDM4EPOLBKMT2AMAPT | |
| SCHEMBL6289025 | 0.71 | ACHE (0.42) | ALDH1A1KDM4EPOLBMAPTACHE | |
| SCHEMBL6289026 | 0.71 | ACHE (0.42) | ALDH1A1KDM4EPOLBMAPTACHE | |
| SCHEMBL6285055 | 0.69 | ACHE (0.40) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL6285053 | 0.69 | ACHE (0.40) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL6285059 | 0.69 | ACHE (0.40) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL6286303 | 0.68 | CALCRL (0.38) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL14373076 | 0.67 | GSK3B (0.42) | ALDH1A1KDM4ETDP1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927294-B1 | Nitrogen-containing heterocycles | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-08-09 | — | — | US | disclosed |