Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | PER2 | O15055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27703810 | 0.72 | KMT2A (0.42) | ALDH1A1HTTSMN1; SMN2DRD2KMT2A | |
| SCHEMBL6287411 | 0.71 | MEN1 (0.42) | CALCRLALDH1A1SMN1; SMN2DRD2DRD4 | |
| SCHEMBL6284373 | 0.69 | KMT2A (0.48) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL6284400 | 0.68 | KDM4E (0.45) | ALDH1A1HTTSMN1; SMN2DRD2DRD4 | |
| SCHEMBL6280465 | 0.68 | ALDH1A1 (0.43) | ALDH1A1HTTSMN1; SMN2DRD2DRD4 | |
| SCHEMBL6289025 | 0.65 | ACHE (0.42) | ALDH1A1DRD2DRD4ACHEKDM4E | |
| SCHEMBL6289026 | 0.65 | ACHE (0.42) | ALDH1A1DRD2DRD4ACHEKDM4E | |
| SCHEMBL6285053 | 0.63 | ACHE (0.40) | CALCRLALDH1A1SMN1; SMN2DRD2DRD4 | |
| SCHEMBL6285055 | 0.63 | ACHE (0.40) | CALCRLALDH1A1SMN1; SMN2DRD2DRD4 | |
| SCHEMBL6285059 | 0.63 | ACHE (0.40) | CALCRLALDH1A1SMN1; SMN2DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927294-B1 | Nitrogen-containing heterocycles | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-08-09 | — | — | US | disclosed |