Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Isophthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.64 |
| ▸ | CA4 | P22748 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 13/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isophthalic Acid SCHEMBL106980 | 0.97 | CA2 (0.67) | CA2CA4CA1ATMTDP1 | |
| Isophthalic Acid SCHEMBL9930796 | 0.95 | CA2 (0.64) | CA2CA4CA1ATMTDP1 | |
| Terephthalic Acid SCHEMBL6856959 | 0.92 | CA2 (0.68) | CA2CA4CA1ATMTDP1 | |
| Isophthalic Acid SCHEMBL161261 | 0.92 | CA2 (0.59) | CA2CA4CA1ATMTDP1 | |
| Isophthalic Acid SCHEMBL23035004 | 0.92 | CA2 (0.59) | CA2CA4CA1ATMTDP1 | |
| Isophthalic Acid SCHEMBL23035003 | 0.92 | CA2 (0.59) | CA2CA4CA1ATMTDP1 | |
| Isophthalic Acid SCHEMBL3684094 | 0.92 | CA2 (0.59) | CA2CA4CA1ATMTDP1 | |
| Isophthalic Acid SCHEMBL25202017 | 0.92 | CA2 (0.59) | CA2CA4CA1ATMTDP1 | |
| Isophthalic Acid SCHEMBL6264265 | 0.92 | CA2 (0.59) | CA2CA4CA1ATMTDP1 | |
| Isophthalic Acid SCHEMBL105996 | 0.92 | CA2 (0.59) | CA2CA4CA1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951913-B2 | Silicone-modified sulphonated comb polymers and preparations, in particular hair cosmetic preparations, based on such silicone-modified sulphonated comb polymers | Beiersdörf AG (DE) | 2005-10-04 | — | — | US | disclosed |
| US-20040072966-A1 | Silicone-modified sulphonated comb polymers and preparations, in particular hair cosmetic preparations, based on such silicone-modified sulphonated comb polymers | BEIERSDORF AG | 2004-04-15 | — | — | US | disclosed |