Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Isophthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 10/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isophthalic Acid SCHEMBL15572636 | 0.95 | CA2 (0.54) | CA2CA4ATMTDP1L3MBTL1 | |
| Isophthalic Acid SCHEMBL106980 | 0.94 | CA2 (0.67) | CA2CA4ATMTDP1L3MBTL1 | |
| Isophthalic Acid SCHEMBL4450604 | 0.94 | CA2 (0.59) | CA2CA4ATMTDP1L3MBTL1 | |
| Isophthalic Acid SCHEMBL11292198 | 0.94 | CA2 (0.59) | CA2CA4ATMTDP1L3MBTL1 | |
| Isophthalic Acid SCHEMBL23035003 | 0.94 | CA2 (0.59) | CA2CA4ATMTDP1L3MBTL1 | |
| Isophthalic Acid SCHEMBL23035004 | 0.94 | CA2 (0.59) | CA2CA4ATMTDP1L3MBTL1 | |
| Isophthalic Acid SCHEMBL105996 | 0.94 | CA2 (0.59) | CA2CA4ATMTDP1L3MBTL1 | |
| Isophthalic Acid SCHEMBL25202017 | 0.94 | CA2 (0.59) | CA2CA4ATMTDP1L3MBTL1 | |
| Isophthalic Acid SCHEMBL3684094 | 0.94 | CA2 (0.59) | CA2CA4ATMTDP1L3MBTL1 | |
| Isophthalic Acid SCHEMBL161261 | 0.94 | CA2 (0.59) | CA2CA4ATMTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1593712-A1 | FLAME-RETARDANT POLYCARBONATE RESIN COMPOSITION | DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-11-09 | — | — | EP | claimed |
| JP-59219332-A | — | — | None | — | — | JP | disclosed |
| WO-2024019466-A1 | ORGANIC-INORGANIC NANOPOROUS ADSORBENT CONTAINING HYDROXY LIGAND AND METHOD FOR PREPARING SAME | 한국생산기술연구원 | 2024-01-25 | — | — | WO | disclosed |
| CN-112029108-B | Nano MOF material and preparation method and application thereof | 曾能 | 2022-05-03 | — | — | CN | disclosed |
| CN-110952161-B | Low-melting-point elastic polyester fiber and preparation method thereof | 扬州富威尔复合材料有限公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-106471061-B | Polylactic acid composition, molded body obtained from polylactic acid composition, and method for producing polylactic acid composition | 帝人株式会社 | 2021-06-08 | — | — | CN | disclosed |
| CN-110952168-B | Low-content organic volatile matter and low-melting-point polyester fiber and preparation method thereof | 扬州富威尔复合材料有限公司 | 2021-05-28 | — | — | CN | disclosed |
| US-11001707-B2 | Polylactic acid composition, formed article obtained from polylactic acid composition, and method for producing polylactic acid composition | TEIJIN LIMITED (JP) | 2021-05-11 | — | — | US | disclosed |
| CN-112029108-A | Nano MOF material and preparation method and application thereof | 曾能 | 2020-12-04 | — | — | CN | disclosed |
| CN-107810231-B | Polymer composition comprising linear low density polyethylene | SABIC环球技术有限责任公司 | 2020-10-16 | — | — | CN | disclosed |
| WO-1993020270-A1 | GASKET MATERIAL | HOLLINGSWORTH & VOSE COMPANY (US) | 1993-10-14 | — | — | WO | disclosed |
| US-5240766-A | Fiber, elastomeric binder and a solid filler | HOLLINGSWORTH & VOSE COMPANY (US) | 1993-08-31 | — | — | US | disclosed |
| US-4490522-A | REACTING POLYHALOGENATED AROMATIC COMPOUND WITH ALKALI METAL SULFIDE IN PRESENCE OF OXYALKYLENE COMPOUND | DAINIPPON INK & CHEMICALS, INC. (JP) | 1984-12-25 | — | — | US | disclosed |
| JP-S59219332-A | PRODUCTION OF POLYPHENYLENE SULFIDE | DAINIPPON INK & CHEM INC | 1984-12-10 | — | — | JP | disclosed |
| EP-0011607-B1 | METALLIC CHROMATE PIGMENT COMPOSITIONS AND PROCESS FOR PREPARING THEM | CIBA-GEIGY AG (CH) | 1981-09-02 | — | — | EP | disclosed |
| US-4247338-A | BLENDING WITH PLASTICIZERS, ZINC, CALCIUM SALTS OF CARBOXYLIC ACIDS | CIBA-GEIGY CORPORATION (US) | 1981-01-27 | — | — | US | disclosed |
| EP-0011607-A1 | Metallic chromate pigment compositions and process for preparing them | CIBA-GEIGY AG (CH) | 1980-05-28 | — | — | EP | disclosed |
| US-3985797-A | Hydroxylation of aromatic compounds | UOP INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3985796-A | Hydroxylation of aromatic compounds | UOP INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3931295-A | Hydroxylation of aromatic compounds | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1976-01-06 | — | — | US | disclosed |