Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Isophthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 14/20 | 0.67 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.67 |
| ▸ | CA1 known ✓ | P00915 | 13/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isophthalic Acid SCHEMBL6280489 | 0.97 | CA2 (0.64) | CA2CA4CA1ATMTDP1 | |
| Isophthalic Acid SCHEMBL9930796 | 0.97 | CA2 (0.64) | CA2CA4CA1ATMTDP1 | |
| Terephthalic Acid SCHEMBL6856959 | 0.95 | CA2 (0.68) | CA2CA4CA1ATMTDP1 | |
| Isophthalic Acid SCHEMBL6264265 | 0.94 | CA2 (0.59) | CA2CA4CA1ATMTDP1 | |
| Isophthalic Acid SCHEMBL23035004 | 0.94 | CA2 (0.59) | CA2CA4CA1ATMTDP1 | |
| Isophthalic Acid SCHEMBL25202017 | 0.94 | CA2 (0.59) | CA2CA4CA1ATMTDP1 | |
| Isophthalic Acid SCHEMBL161261 | 0.94 | CA2 (0.59) | CA2CA4CA1ATMTDP1 | |
| Isophthalic Acid SCHEMBL23035003 | 0.94 | CA2 (0.59) | CA2CA4CA1ATMTDP1 | |
| Isophthalic Acid SCHEMBL105996 | 0.94 | CA2 (0.59) | CA2CA4CA1ATMTDP1 | |
| Isophthalic Acid SCHEMBL3684094 | 0.94 | CA2 (0.59) | CA2CA4CA1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1469 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111074377-B | Eccentric sheath-core type colored fiber, preparation method and preparation device thereof | 中国纺织科学研究院有限公司 | 2026-05-22 | — | — | CN | claimed |
| CN-224252140-U | Crystallization device for producing isophthalic acid-5-sodium sulfonate | 德州瑞桥化工有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122060173-A | Preparation method of aqueous polyamide carbon fiber sizing agent | 迈臻高分子新材料(上海)有限公司 | 2026-05-19 | — | — | CN | claimed |
| US-12630710-B1 | 1,5-pentanediol-based polyester compositions with enhanced crystallization rates and methods of manufacture | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2026-05-19 | — | — | US | claimed |
| CN-120132811-A | Application of zinc-based microporous metal organic framework material in formaldehyde removal | 北京工业大学 | 2025-06-13 | — | — | CN | claimed |
| CN-119912683-A | Polyamide, preparation method thereof, sizing agent and application thereof | 中国石油化工股份有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-119774947-A | Pumping foam concrete mixture and preparation method thereof | 普宁市吉润混凝土有限公司 | 2025-04-08 | — | — | CN | claimed |
| CN-119775545-A | Water-soluble polyester resin, plasma etching protection liquid containing same, and preparation method and application thereof | 深圳市化讯半导体材料有限公司 | 2025-04-08 | — | — | CN | claimed |
| CN-119777030-A | Degradable parallel composite regenerated high-elastic polyester staple fiber and preparation method thereof | 宁波大发新材料有限公司 | 2025-04-08 | — | — | CN | claimed |
| CN-119735795-A | Regenerated polyester pore-forming agent and preparation method and application thereof | 东华大学 | 2025-04-01 | — | — | CN | claimed |
| EP-1114095-A1 | NUCLEATING AGENT FOR POLYESTERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-07-11 | — | — | EP | claimed |
| US-6245844-B1 | MONO-SODIUM SALT OF A DICARBOXYLIC ACID | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-06-12 | — | — | US | claimed |
| WO-2000017265-A1 | NUCLEATING AGENT FOR POLYESTERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-03-30 | — | — | WO | claimed |
| US-5756635-A | DRAWING FIBERS FROM SOLVENTS, REMOVAL AND DRYING | RHONE-POULENC FIBRES (FR) | 1998-05-26 | — | — | US | claimed |
| EP-0638549-A1 | A 4,4'-dihydroxydiphenylsulfone monomer composition and a process for production thereof | NICCA CHEMICAL CO., LTD. (JP) | 1995-02-15 | — | — | EP | claimed |
| US-4834891-A | ALKALI METAL PHTHALATE, GLASS | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) | 1989-05-30 | — | — | US | claimed |
| EP-0078361-B1 | SYNTHETIC HOT FORGING LUBRICANTS AND PROCESS | PENNWALT CORPORATION (US) | 1985-11-21 | — | — | EP | claimed |
| US-4454050-A | ALKALI METAL SALT OF AN AROMATIC POLYCARBOXYLIC ACID, AND OF AN ALIPHATIC POLYCARBOXYLIC ACID | PENNWALT CORPORATION (US) | 1984-06-12 | — | — | US | claimed |
| US-4409113-A | Synthetic hot forging lubricants and process | PENNWALT CORPORATION (US) | 1983-10-11 | — | — | US | claimed |
| EP-0078361-A1 | Synthetic hot forging lubricants and process | PENNWALT CORPORATION (US) | 1983-05-11 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630710-B1 | 1,5-pentanediol-based polyester compositions with enhanced crystallization rates and methods of manufacture | GRIN2D, SMCHD1, GRIN2C | CA2 55/4885CA4 416/4885CA1 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.