Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 4/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235288 | 0.72 | NPC1 (0.40) | MITFTDP1ALDH1A1HSD17B10ELANE | |
| SCHEMBL2517288 | 0.70 | ALDH1A1 (0.46) | PAX8TDP1L3MBTL1ALDH1A1CYP2A6 | |
| SCHEMBL28548156 | 0.69 | CYP1A2 (0.44) | TDP1ALDH1A1CYP2A6HSD17B10ELANE | |
| SCHEMBL5080818 | 0.67 | — | — | |
| SCHEMBL2544 | 0.67 | — | — | |
| SCHEMBL207427 | 0.65 | MAOA (0.47) | TDP1ALDH1A1HSD17B10MAOAMAOB | |
| SCHEMBL2518542 | 0.64 | ALDH1A1 (0.50) | PAX8TDP1L3MBTL1ALDH1A1CYP2A6 | |
| SCHEMBL3680624 | 0.64 | ALDH1A1 (0.34) | TDP1ALDH1A1CYP2A6TSHRHSD17B10 | |
| Isocoumarin SCHEMBL31031794 | 0.64 | PTGES (0.47) | PTGESMITFPAX8TDP1L3MBTL1 | |
| Isocoumarin SCHEMBL76183 | 0.64 | PTGES (0.47) | PTGESMITFPAX8TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2885 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109069523-B | Mannan-oligosaccharide compound and application thereof as anti-RNA virus drug | 扬州蓝色生物医药科技有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-106795174-B | Antiviral active diazacyclospirodiketopiperazine alkaloid derivative and preparation method thereof | 扬州蓝色生物医药科技有限公司 | 2020-04-28 | — | — | CN | claimed |
| US-10238680-B2 | D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease | IDENIX PHARMACEUTICALS LLC (US) | 2019-03-26 | — | — | US | claimed |
| EP-2852605-B1 | 3',5'-CYCLIC PHOSPHATE PRODRUGS FOR HCV INFECTION | IDENIX PHARMACEUTICALS LLC (US) | 2018-01-31 | — | — | EP | claimed |
| US-20160280729-A1 | CYCLOPENTANE AND CYCLOPENTENE NUCLEOSIDE ANALOGS FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS LLC (US) | 2016-09-29 | — | — | US | claimed |
| US-20160082030-A1 | D-AMINO ACID PHOSPHORAMIDATE PRONUCLEOTIDES OF HALOGENO PYRIMIDINE COMPOUNDS FOR LIVER DISEASE | UNIVERSITE DE MONTPELLIER (FR) | 2016-03-24 | — | — | US | claimed |
| WO-2015077360-A2 | CYCLOPENTANE AND CYCLOPENTENE NUCLEOSIDE ANALOGS FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS, INC. (US) | 2015-05-28 | — | — | WO | claimed |
| EP-1660464-B1 | CASPASE INHIBITORS CONTAINING ISOXAZOLINE RING | LG LIFE SCIENCES LTD (KR) | 2015-02-25 | — | — | EP | claimed |
| CN-104356006-A | Benzyl amines, a process for their production and their use as anti-inflammtory agents | Bayer Pharma AG | 2015-02-18 | — | — | CN | claimed |
| US-20150037282-A1 | D-AMINO ACID PHOSPHORAMIDATE PRONUCLEOTIDES OF HALOGENO PYRIMIDINE COMPOUNDS FOR LIVER DISEASE | IDENIX PHARMACEUTICALS, INC. | 2015-02-05 | — | — | US | claimed |
| WO-2002002505-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |
| WO-2002002520-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |
| EP-1133487-A1 | SCAVENGER COMPOUNDS | YISSUM RESEARCH AND DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2001-09-19 | — | — | EP | claimed |
| EP-0720601-B1 | GASTRIN AND CCK RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2000-10-25 | — | — | EP | claimed |
| WO-2000031060-A1 | SCAVENGER COMPOUNDS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2000-06-02 | — | — | WO | claimed |
| US-5939437-A | AMIDE COMPOUNDS AS NEUROPEPTIDES AS APPETITE REGULATORS, ANXIOLYTIC ACTIVITY AND ANTICARCINOGENIC AGENTS | JAMES BLACK FOUNDATION LIMITED (GB) | 1999-08-17 | — | — | US | claimed |
| US-5919829-A | Gastrin and cck receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 1999-07-06 | — | — | US | claimed |
| US-5795907-A | Gastin and CCK receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 1998-08-18 | — | — | US | claimed |
| EP-0289430-B1 | SWEETENERS DERIVED FROM GUANIDINOACETIC AND ETHANAMIDINOACETIC ACIDS, THEIR USES AND COMPOSITIONS CONTAINING THESE SWEETENERS | UNIVERSITE CLAUDE BERNARD - LYON 1 (FR) | 1992-04-08 | — | — | EP | claimed |
| CN-88100129-A | The preparation method of sweeting agent guanidoacetic acid and ethanamidine guanidine-acetic acid derivative and the prescription that contains this class sweeting agent | — | 1988-07-27 | — | — | CN | claimed |