Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.40 |
| ▸ | PTPRB | P23467 | 3/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.40 |
| ▸ | PTPRC | P08575 | 3/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10247270 | 0.72 | PTPN1 (0.49) | PTPN1TSHRL3MBTL1MAPTMAPK1 | |
| SCHEMBL5664859 | 0.70 | L3MBTL1 (0.44) | PTPN1L3MBTL1MAPTMAPK1TDP1 | |
| SCHEMBL4049346 | 0.69 | CCNB2 (0.43) | PTPN1L3MBTL1MAPTMAPK1TDP1 | |
| SCHEMBL19755568 | 0.69 | LMNA (0.53) | PTPN1TSHRL3MBTL1MAPTTDP1 | |
| SCHEMBL6702230 | 0.68 | LMNA (0.40) | PTPN1ALPGPTK2BTSHRL3MBTL1 | |
| SCHEMBL5665055 | 0.68 | POLB (0.49) | PTPN1L3MBTL1LMNAPOLBGAA | |
| SCHEMBL10247058 | 0.67 | PTPN1 (0.47) | PTPN1TSHRL3MBTL1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL18838680 | 0.66 | L3MBTL1 (0.42) | PTPN1TSHRL3MBTL1MAPTMAPK1 | |
| SCHEMBL5665433 | 0.65 | L3MBTL1 (0.42) | PTPN1TSHRL3MBTL1MAPTMAPK1 | |
| SCHEMBL82592 | 0.65 | THRB (0.43) | PTPN1L3MBTL1MAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606295-A1 | HETEROARYL PHOSPHONATES, COMPOSITIONS CONTAINING THEM AND METHODS OF TREATMENT OF VARIOUS DISORDERS USING THEM | Medicure Inc. (CA) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004083222-A1 | NOVEL HETEROARYL PHOSPHONATES AS CARDIOPROTECTIVE AGENTS | MEDICURE INC. (CA) | 2004-09-30 | — | — | WO | disclosed |