Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5666900 | 0.85 | LMNA (0.36) | LMNAHPGDALDH1A1TSHRHTT | |
| SCHEMBL10247058 | 0.74 | PTPN1 (0.47) | LMNAHPGDTSHRHTTMAPK1 | |
| SCHEMBL10247270 | 0.73 | PTPN1 (0.49) | LMNAHPGDALDH1A1TSHRHTT | |
| SCHEMBL5665055 | 0.72 | POLB (0.49) | LMNAPTPN1POLBGAAGLRA1 | |
| SCHEMBL5665433 | 0.72 | L3MBTL1 (0.42) | LMNAHPGDTSHRHTTMAPK1 | |
| SCHEMBL5665324 | 0.70 | L3MBTL1 (0.43) | LMNAHPGDALDH1A1HTTMAPK1 | |
| SCHEMBL5666549 | 0.70 | PNPO (0.38) | LMNAHPGDALDH1A1KDM4EMEN1 | |
| SCHEMBL6280878 | 0.68 | PTPN1 (0.40) | LMNAHPGDALDH1A1TSHRMAPK1 | |
| SCHEMBL82592 | 0.66 | THRB (0.43) | LMNAHPGDALDH1A1HTTMAPK1 | |
| SCHEMBL5664859 | 0.66 | L3MBTL1 (0.44) | LMNAHPGDALDH1A1HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040186077-A1 | Novel heteroaryl phosphonates as cardioprotective agents | MEDICURE INTERNATIONAL INC. (BB) | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186077-A1 | Novel heteroaryl phosphonates as cardioprotective agents | TNNT2, TNNI3, ADRB3 | LMNA 1102/4885HPGD 836/4885ALDH1A1 3091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.