Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1831948 | 0.79 | HIF1A (0.41) | HIF1ACHRNB4CHRNA3CYP2D6CHRNB2 | |
| SCHEMBL11846749 | 0.79 | HIF1A (0.41) | HIF1ACHRNB4CHRNA3CYP2D6CHRNB2 | |
| SCHEMBL596253 | 0.78 | HIF1A (0.39) | HIF1ACHRNB4CHRNA3CYP2D6CHRNB2 | |
| SCHEMBL1702299 | 0.74 | HIF1A (0.37) | HIF1ACYP2D6CALM1 | |
| SCHEMBL6926932 | 0.74 | SIGMAR1 (0.46) | HIF1ACYP2D6 | |
| Hydrochloric Acid SCHEMBL10944858 | 0.73 | SIGMAR1 (0.44) | HIF1A | |
| SCHEMBL8914673 | 0.72 | MEN1 (0.41) | HIF1ACHRNB2CHRNA4 | |
| SCHEMBL10841967 | 0.70 | SIGMAR1 (0.59) | — | |
| Hydrochloric Acid SCHEMBL10843617 | 0.69 | SIGMAR1 (0.57) | — | |
| SCHEMBL7248999 | 0.68 | HIF1A (0.38) | HIF1ACYP2D6CHRNB2CHRNA4CALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005113573-A2 | METHOD OF SUPPORT-BASED CHEMICAL SYNTHESIS | MIXTURE SCIENCES, INC. (US) | 2005-12-01 | — | — | WO | disclosed |
| US-20050261474-A1 | Method of support-based chemical synthesis | MIXTURE SCIENCES, INC. | 2005-11-24 | — | — | US | disclosed |
| US-20050112693-A1 | Diketodiazacyclic compounds, diazacyclic compounds and combinatorial libraries thereof | NEFZI ADEL (US) | 2005-05-26 | — | — | US | disclosed |
| US-6809202-B2 | SYNTHETIC PEPTIDES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES | 2004-10-26 | — | — | US | disclosed |
| US-20030120066-A1 | Synthetic peptides | NEFZI ADEL (US) | 2003-06-26 | — | — | US | disclosed |
| US-6441172-B1 | DI- AND TRI-SUBSTITUTED-1,4-DIAZACYCLIC COMPOUNDS | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES | 2002-08-27 | — | — | US | disclosed |
| US-4139621-A | TRANQUILIZERS | BEECHAM GROUP LIMITED (GB) | 1979-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050112693-A1 | Diketodiazacyclic compounds, diazacyclic compounds and combinatorial libraries thereof | DHPS, DCK, DAZAP1 | HIF1A 3111/4885CHRNB4 3425/4885CHRNA3 3008/4885 |
| US-20050261474-A1 | Method of support-based chemical synthesis | CYP2F1, CYP4F3, CYP4F2 | HIF1A 2015/4885CHRNB4 4582/4885CHRNA3 4846/4885 |
| US-20030120066-A1 | Synthetic peptides | VIP, NGLY1, GRPR | HIF1A 4139/4885CHRNB4 3579/4885CHRNA3 4291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.