Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mannitol SCHEMBL7249316 | 0.77 | LMNA (0.61) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Mannitol SCHEMBL20572201 | 0.77 | LMNA (0.69) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Mannitol SCHEMBL3887158 | 0.77 | LMNA (0.69) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Sorbitol SCHEMBL3227835 | 0.77 | LMNA (0.69) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL2321352 | 0.75 | LMNA (0.41) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL264710 | 0.75 | LMNA (0.41) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL3229856 | 0.75 | LMNA (0.41) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL2317860 | 0.75 | LMNA (0.41) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL2429499 | 0.75 | LMNA (0.41) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Sorbitol SCHEMBL15993963 | 0.74 | LMNA (0.65) | LMNAL3MBTL1TDP1KDM4EPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558755-A2 | METHOD OF DETERMINING SPECIFIC GROUPS FORMING HEPARINS | Aventis Pharma S.A. (FR) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004027087-A2 | METHOD OF DETERMINING SPECIFIC GROUPS FORMING HEPARINS | AVENTIS PHARMA S.A. (FR) | 2004-04-01 | — | — | WO | disclosed |