SCHEMBL6281357

SCHEMBL6281357

Cc1cc(Cn2nnnc2C)ccc1[N+](=O)[O-]

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 1/20 0.40
PGR P06401 1/20 0.40
AR P10275 1/20 0.40
MAPT P10636 1/20 0.40
TSHR P16473 2/20 0.39
HSD17B10 Q99714 1/20 0.39
HPGD P15428 1/20 0.39
ALDH1A1 P00352 5/20 0.39
POLB P06746 2/20 0.39
CYP1A2 P05177 2/20 0.39
MGAM O43451 1/20 0.39
AMY1A P0DUB6 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
CYP2C19 P33261 1/20 0.37
BLM P54132 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
NPC1 O15118 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5906128 0.80 P2RX7 (0.53) ALDH1A1
SCHEMBL5905990 0.79 POLB (0.53) NR3C1PGRARTSHRHPGD
SCHEMBL5906088 0.79 HTT (0.52) MAPTALDH1A1POLBGAAL3MBTL1
SCHEMBL5906039 0.77 MAPT (0.39) NR3C1PGRARMAPTTSHR
SCHEMBL5906184 0.77 TSHR (0.41) NR3C1PGRARMAPTTSHR
SCHEMBL5905875 0.77 POLB (0.67) POLBL3MBTL1
SCHEMBL5906347 0.76 LMNA (0.48) MAPTTSHRALDH1A1POLBGAA
SCHEMBL5905969 0.76 BLM (0.38) NR3C1PGRARMAPTTSHR
SCHEMBL5906038 0.76 L3MBTL1 (0.48) MAPTTSHRHSD17B10HPGDALDH1A1
SCHEMBL5906284 0.76 MEN1 (0.47) NR3C1PGRARMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1606271-A1 INSECTICIDAL PHTHALAMIDE DERIVATIVES Bayer CropScience AG (DE) 2005-12-21 EP disclosed
WO-2004080984-A1 INSECTICIDAL PHTHALAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2004-09-23 WO disclosed