SCHEMBL6281734

SCHEMBL6281734

N#Cc1cccc(-c2cc3ccccc3c(-c3cccc4ccccc34)c2-c2cccc(C#N)c2C#N)c1C#N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
MCL1 Q07820 1/20 0.42
KDM4E B2RXH2 2/20 0.41
PIM1 P11309 3/20 0.39
GPR84 Q9NQS5 1/20 0.37
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 2/20 0.36
HSD17B10 Q99714 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
ALOX15 P16050 1/20 0.35
HSP90AA1 P07900 1/20 0.35
HSP90AB1 P08238 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
CASP1 P29466 1/20 0.35
HIF1A Q16665 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL769609 0.85 CA1 (0.46) CA1CA2MCL1KDM4EPIM1
SCHEMBL30135211 0.84 CA1 (0.46) CA1CA2MCL1KDM4EPIM1
SCHEMBL769553 0.83 CA1 (0.55) CA1CA2MCL1KDM4EPIM1
SCHEMBL29489130 0.81 MCL1 (0.47) CA1CA2MCL1KDM4EPIM1
SCHEMBL29663473 0.78 GPR84 (0.53) KDM4EGPR84ALDH1A1HPGDHSD17B10
SCHEMBL29110490 0.77 MCL1 (0.49) CA1CA2MCL1KDM4EPIM1
SCHEMBL29039496 0.74 CA1 (0.50) CA1CA2MCL1KDM4EPIM1
SCHEMBL32689890 0.74 ALDH1A1 (0.48) KDM4EGPR84CYP11B1ALDH1A1HPGD
SCHEMBL13170778 0.74 CA1 (0.55) CA1CA2MCL1KDM4EPIM1
SCHEMBL16786545 0.73 PIM1 (0.51) CA1CA2MCL1KDM4EPIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2005200310-A PHTHALOCYANINE DERIVATIVE HAVING CROWN ETHER RING IN MOLECULE AND INTERMEDIATE THEREFOR NAGAOKA UNIV OF TECHNOLOGY 2005-07-28 JP disclosed