Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246786 | 0.82 | TSHR (0.39) | ALDH1A1TP53TSHR | |
| SCHEMBL2361024 | 0.79 | — | — | |
| SCHEMBL4644506 | 0.76 | — | — | |
| SCHEMBL9036369 | 0.76 | — | — | |
| SCHEMBL11516458 | 0.73 | — | — | |
| Trichloroacetic Acid SCHEMBL10493657 | 0.70 | TSHR (1.00) | ALDH1A1TP53TSHRTDP1 | |
| SCHEMBL20973 | 0.70 | — | — | |
| SCHEMBL134778 | 0.70 | ALDH1A1 (0.54) | ALDH1A1TP53TSHRTDP1 | |
| SCHEMBL206379 | 0.70 | — | — | |
| Trichloroacetic Acid SCHEMBL38661501 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6933288-B2 | Pyranosyl cytosines: pharmaceutical formulations and methods | ISIS PHARMACEUTICALS, INC. | 2005-08-23 | — | — | US | disclosed |
| US-20030216575-A1 | Novel pyranosyl cytosines: pharmaceutical formulations and methods | ISIS PHARMACEUTICALS, INC. | 2003-11-20 | — | — | US | disclosed |
| WO-2003066633-A1 | NOVEL PYRANOSYL CYTOSINES: PHARMACEUTICAL FORMULATIONS AND METHODS | ISIS PHARMACEUTICALS, INC. (US) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216575-A1 | Novel pyranosyl cytosines: pharmaceutical formulations and methods | RNGTT, NOP2, RNMT | ALDH1A1 3286/4885TP53 1394/4885TSHR 4596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.