SCHEMBL6282684

SCHEMBL6282684

CC(C)(C)c1cccc(N)c1O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.70
GABRA1 P14867 1/20 0.59
GABRB2 P47870 1/20 0.59
ALOX12 P18054 1/20 0.48
ALDH1A1 P00352 4/20 0.48
TSHR P16473 3/20 0.48
TDP1 Q9NUW8 1/20 0.48
NPSR1 Q6W5P4 1/20 0.44
MMP2 P08253 1/20 0.42
CA1 P00915 1/20 0.39
CYP3A4 P08684 1/20 0.39
PIK3CA P42336 1/20 0.39
GAA P10253 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
POLB P06746 1/20 0.38
TYR P14679 1/20 0.38
MAPT P10636 2/20 0.38
ALOX5AP P20292 2/20 0.38
FEN1 P39748 2/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL4969015 0.98 CA2 (0.67) CA2GABRA1GABRB2ALOX12ALDH1A1
SCHEMBL564371 0.86 CA2 (0.50) CA2GABRA1GABRB2ALOX12ALDH1A1
Hydrazine SCHEMBL4336034 0.83 CA2 (0.90) CA2GABRA1GABRB2ALOX12ALDH1A1
Methylamine SCHEMBL27452203 0.83 CA2 (0.90) CA2GABRA1GABRB2ALOX12ALDH1A1
SCHEMBL38598 0.83 CA2 (1.00) CA2GABRA1GABRB2ALOX12ALDH1A1
Hydrazine SCHEMBL28112820 0.81 CA2 (0.85) CA2GABRA1GABRB2ALOX12ALDH1A1
Hydrochloric Acid SCHEMBL7076174 0.80 CA2 (0.94) CA2GABRA1GABRB2ALOX12ALDH1A1
SCHEMBL31622310 0.80 CA2 (0.94) CA2GABRA1GABRB2ALOX12ALDH1A1
SCHEMBL29189109 0.80 CA2 (0.94) CA2GABRA1GABRB2ALOX12ALDH1A1
SCHEMBL22444875 0.80 CA2 (0.94) CA2GABRA1GABRB2ALOX12ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10920017-B2 Polyimide resin and resin composition KANEKA CORPORATION (JP) 2021-02-16 US disclosed
US-20190263968-A1 POLYIMIDE RESIN AND RESIN COMPOSITION KANEKA CORPORATION (JP) 2019-08-29 US disclosed
US-10175574-B2 Coloring composition, and cured film, color filter, pattern forming method, method for manufacturing color filter, solid-state imaging device, image display device, and dye multimer, each using the coloring composition FUJIFILM CORPORATION (JP) 2019-01-08 US disclosed
EP-2238186-B1 ETHYLENE/ALPHA-OLEFIN BLOCK INTERPOLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-11-28 EP disclosed
CN-105142605-B 1, 2-alkane polyol-containing composition 大阪有机化学工业株式会社 2018-06-08 CN disclosed
US-20180095374-A1 MIXTURE, TONER, AND DISPERSION CANON KABUSHIKI KAISHA (JP) 2018-04-05 US disclosed
US-20180095374-A1 MIXTURE, TONER, AND DISPERSION CANON KABUSHIKI KAISHA (JP) 2018-04-05 US disclosed
US-9795549-B2 1,2-alkane polyol-containing composition OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) 2017-10-24 US disclosed
US-9671687-B2 Coloring composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, and image display device FUJIFILM CORPORATION (JP) 2017-06-06 US disclosed
US-20160327858-A1 COLORING COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING DEVICE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-11-10 US disclosed
US-20160327858-A1 COLORING COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING DEVICE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-11-10 US disclosed
US-20160045414-A1 1,2-ALKANE POLYOL-CONTAINING COMPOSITION OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) 2016-02-18 US disclosed
EP-2985017-A1 1,2-ALKANE POLYOL-CONTAINING COMPOSITION Osaka Organic Chemical Ind., Ltd. (JP) 2016-02-17 EP disclosed
US-20160004154-A1 RADIATION-SENSITIVE COLORED COMPOSITIONS, CURED COLORED FILMS, COLOR FILTERS, PROCESSES FOR FORMING COLORED PATTERNS, PROCESSES FOR PREPARING COLOR FILTERS, SOLID-STATE IMAGE SENSORS AND LIQUID CRYSTAL DISPLAY DEVICES FUJIFILM CORPORATION (JP) 2016-01-07 US disclosed
CN-105142605-A 1, 2-alkane polyol-containing composition OSAKA ORGANIC CHEM IND 2015-12-09 CN disclosed
US-6969711-B2 Cyclic diamine compounds and medicine containing the same KOWA COMPANY, LTD. (JP) 2005-11-29 US disclosed
EP-0987254-B1 NOVEL CYCLIC DIAMINE COMPOUNDS AND MEDICINE CONTAINING THE SAME KOWA CO (JP) 2004-12-22 EP disclosed
US-20040038987-A1 Novel cyclic diamine compounds and medicine containing the same KOWA COMPANY, LTD. (JP) 2004-02-26 US disclosed
EP-0987254-A1 NOVEL CYCLIC DIAMINE COMPOUNDS AND MEDICINE CONTAINING THE SAME Kowa Co., Ltd. (JP) 2000-03-22 EP disclosed
US-4208513-A Benzoxazolyl-phenylstilbenes, processes for producing them, and their use as optical brighteners CIBA-GEIGY CORPORATION (US) 1980-06-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040038987-A1 Novel cyclic diamine compounds and medicine containing the same LCAT, ACAT2, ACAT1 CA2 726/4885GABRA1 3225/4885GABRB2 3687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.