SCHEMBL564371

SCHEMBL564371

CC(C)(c1cccc(N)c1O)c1cccc(N)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.50
GABRA1 P14867 2/20 0.43
GABRB2 P47870 2/20 0.43
MMP2 P08253 1/20 0.42
TSHR P16473 4/20 0.39
CYP3A4 P08684 3/20 0.39
PIK3CA P42336 1/20 0.39
ALDH1A1 P00352 5/20 0.38
TDP1 Q9NUW8 2/20 0.38
ALOX15 P16050 2/20 0.37
ALOX12 P18054 1/20 0.36
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CD44 P16070 1/20 0.34
PKM P14618 2/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6282684 0.86 CA2 (0.70) CA2GABRA1GABRB2MMP2TSHR
SCHEMBL565208 0.86 ESR1 (0.47) CA2GABRA1GABRB2MMP2TSHR
Bromide SCHEMBL4969015 0.84 CA2 (0.67) CA2GABRA1GABRB2MMP2TSHR
SCHEMBL6756206 0.77 MMP2 (0.42) CA2GABRA1GABRB2MMP2TSHR
SCHEMBL103733 0.77 MMP2 (0.42) CA2GABRA1GABRB2MMP2TSHR
SCHEMBL23071530 0.76 CA2 (0.85) CA2GABRA1GABRB2TSHRALDH1A1
SCHEMBL8512559 0.76 CD44 (0.48) CA2GABRA1GABRB2TSHRCYP3A4
SCHEMBL986029 0.76 CA2 (0.54) CA2GABRA1GABRB2MMP2TSHR
SCHEMBL895143 0.75 CYP3A4 (0.47) CA2TSHRCYP3A4PIK3CAALDH1A1
SCHEMBL29361007 0.74 GABRA1 (0.75) CA2GABRA1GABRB2TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 EP disclosed
US-20040152862-A1 Optical resins and applications thereof HITACHI CHEMICAL CO., LTD. (JP) 2004-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 CA2 1653/4885GABRA1 1019/4885GABRB2 1083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.