Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4486342 | 0.81 | SOAT1 (0.46) | CYP2C9CYP2C19CYP1A2SOAT1MAPT | |
| SCHEMBL13755905 | 0.76 | SOAT1 (0.35) | CYP2C9CYP2C19CYP1A2SOAT1MAPT | |
| SCHEMBL4985295 | 0.68 | SOAT1 (0.50) | CYP2C9CYP2C19CYP1A2SOAT1GAA | |
| SCHEMBL4492754 | 0.68 | SOAT1 (0.47) | CYP2C9CYP2C19CYP1A2SOAT1MAPT | |
| SCHEMBL4985802 | 0.68 | RXFP1 (0.40) | CYP1A2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6278875 | 0.67 | SOAT1 (0.38) | CYP2C9CYP2C19CYP1A2SOAT1MAPT | |
| SCHEMBL14565845 | 0.67 | SOAT1 (0.46) | CYP2C9CYP2C19CYP1A2SOAT1MAPT | |
| SCHEMBL9000543 | 0.67 | ALDH1A1 (0.49) | SOAT1MAPTALDH1A1LMNAGAA | |
| SCHEMBL4990313 | 0.67 | SOAT1 (0.46) | SOAT1KMT2AGAARXFP1MAPK1 | |
| SCHEMBL4984257 | 0.67 | SOAT1 (0.46) | SOAT1KMT2AGAARXFP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6969711-B2 | Cyclic diamine compounds and medicine containing the same | KOWA COMPANY, LTD. (JP) | 2005-11-29 | — | — | US | disclosed |
| US-20040038987-A1 | Novel cyclic diamine compounds and medicine containing the same | KOWA COMPANY, LTD. (JP) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038987-A1 | Novel cyclic diamine compounds and medicine containing the same | LCAT, ACAT2, ACAT1 | CYP2C9 1170/4885CYP2C19 2233/4885CYP1A2 872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.