Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 6/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4492754 | 0.87 | SOAT1 (0.47) | SOAT1RXFP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4985295 | 0.86 | SOAT1 (0.50) | SOAT1RXFP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9000543 | 0.85 | ALDH1A1 (0.49) | SOAT1ALDH1A1KDM4EMAPTTP53 | |
| SCHEMBL14565845 | 0.85 | SOAT1 (0.46) | SOAT1RXFP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4984257 | 0.84 | SOAT1 (0.46) | SOAT1RXFP1KMT2AGAA | |
| SCHEMBL4990313 | 0.84 | SOAT1 (0.46) | SOAT1RXFP1KMT2AGAA | |
| SCHEMBL32667998 | 0.83 | CYP1A2 (0.50) | SOAT1CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6282771 | 0.81 | CYP2C9 (0.34) | SOAT1RXFP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13755905 | 0.81 | SOAT1 (0.35) | SOAT1RXFP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4985802 | 0.80 | RXFP1 (0.40) | RXFP1CYP1A2ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1627875-B1 | METHOD FOR PRODUCING CYCLIC DIAMINE DERIVATIVE OR SALT THEREOF | KOWA CO (JP) | 2013-07-31 | — | — | EP | disclosed |
| EP-1460065-B1 | PROCESSES FOR PRODUCTION OF CYCLIC DIAMINE COMPOUNDS OR SALTS THEREOF | KOWA CO (JP) | 2012-12-05 | — | — | EP | disclosed |
| US-7576203-B2 | Method for producing cyclic diamine derivative | KOWA CO., LTD. (JP) | 2009-08-18 | — | — | US | disclosed |
| US-7576203-B2 | Method for producing cyclic diamine derivative | KOWA CO., LTD. (JP) | 2009-08-18 | — | — | US | disclosed |
| US-7576203-B2 | Method for producing cyclic diamine derivative | KOWA CO., LTD. (JP) | 2009-08-18 | — | — | US | disclosed |
| US-7560547-B2 | Hydroxyalkyl cyclic diamine compounds | KOWA CO., LTD. (JP) | 2009-07-14 | — | — | US | disclosed |
| US-7560547-B2 | Hydroxyalkyl cyclic diamine compounds | KOWA CO., LTD. (JP) | 2009-07-14 | — | — | US | disclosed |
| US-7459552-B2 | Method for producing cyclic diamine derivative or salt thereof | KOWA CO., LTD. (JP) | 2008-12-02 | — | — | US | disclosed |
| US-7414066-B2 | Amide compounds and medications containing the same technical field | KOWA COMPANY LTD. (JP) | 2008-08-19 | — | — | US | disclosed |
| US-7393866-B2 | Amide compounds and medications containing the same | KOWA COMPANY, LTD. (JP) | 2008-07-01 | — | — | US | disclosed |
| US-6969711-B2 | Cyclic diamine compounds and medicine containing the same | KOWA COMPANY, LTD. (JP) | 2005-11-29 | — | — | US | disclosed |
| US-20050131002-A1 | Novel amide compounds and medications containing the same | KOWA COMPANY LTD. (JP) | 2005-06-16 | — | — | US | disclosed |
| US-20050131001-A1 | Novel amide compounds and medications containing the same technical field | KOWA COMPANY LTD. (JP) | 2005-06-16 | — | — | US | disclosed |
| US-20050032814-A1 | Process for production of cyclic diamine compounds or salts thereof | KOWA CO., LTD. (JP) | 2005-02-10 | — | — | US | disclosed |
| US-6849647-B1 | Amide compounds and medications containing the same technical field | KOWA COMPANY, LTD. (JP) | 2005-02-01 | — | — | US | disclosed |
| EP-0987254-B1 | NOVEL CYCLIC DIAMINE COMPOUNDS AND MEDICINE CONTAINING THE SAME | KOWA CO (JP) | 2004-12-22 | — | — | EP | disclosed |
| EP-1460065-A1 | PROCESSES FOR PRODUCTION OF CYCLIC DIAMINE COMPOUNDS OR SALTS THEREOF | Kowa Co., Ltd. (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-20040038987-A1 | Novel cyclic diamine compounds and medicine containing the same | KOWA COMPANY, LTD. (JP) | 2004-02-26 | — | — | US | disclosed |
| EP-0987254-A1 | NOVEL CYCLIC DIAMINE COMPOUNDS AND MEDICINE CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2000-03-22 | — | — | EP | disclosed |
| EP-0979823-A1 | NOVEL AMIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | Kowa Company Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131001-A1 | Novel amide compounds and medications containing the same technical field | ACAT2, SULT2A1, ACAT1 | SOAT1 9/4885RXFP1 437/4885CYP1A2 392/4885 |
| US-20050032814-A1 | Process for production of cyclic diamine compounds or salts thereof | SRM, DDC, QDPR | SOAT1 3634/4885RXFP1 2541/4885CYP1A2 595/4885 |
| US-20050131002-A1 | Novel amide compounds and medications containing the same | ACAT2, SULT2A1, ACAT1 | SOAT1 23/4885RXFP1 526/4885CYP1A2 490/4885 |
| US-20040038987-A1 | Novel cyclic diamine compounds and medicine containing the same | LCAT, ACAT2, ACAT1 | SOAT1 5/4885RXFP1 2019/4885CYP1A2 872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.