Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417280 | 1.00 | THRB (0.39) | THRBDPP4F2TSHRALDH1A1 | |
| SCHEMBL12761433 | 0.91 | THRB (0.39) | THRBALDH1A1HTTGAATAAR1 | |
| SCHEMBL14535854 | 0.89 | THRB (0.34) | THRBDPP4F2TSHRALDH1A1 | |
| SCHEMBL2839765 | 0.82 | HTT (0.41) | DPP4TSHRHTTSLC6A2SLC6A4 | |
| SCHEMBL29980071 | 0.80 | ADRA2A (0.42) | ALDH1A1TAAR1LMNAADRA2AADRA2C | |
| SCHEMBL9232899 | 0.80 | ADRA2A (0.42) | ALDH1A1TAAR1LMNAADRA2AADRA2C | |
| SCHEMBL11069443 | 0.78 | KMT2A (0.51) | ALDH1A1HTTSLC6A3KMT2ALMNA | |
| SCHEMBL10582605 | 0.78 | CES2 (0.37) | DPP4F2TSHRSLC6A2SLC6A4 | |
| SCHEMBL28751443 | 0.78 | MIF (0.33) | DPP4F2TSHRALDH1A1SLC6A2 | |
| Iodide SCHEMBL8532159 | 0.77 | HIF1A (0.34) | THRBALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6967229-B2 | Carbon-carbon initiators for use in golf balls | ACUSHNET COMPANY (US) | 2005-11-22 | — | — | US | claimed |
| US-20050009992-A1 | Carbon-carbon initiators for use in golf balls | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2005-01-13 | — | — | US | claimed |
| US-9056227-B2 | Golf ball comprising a core having a shallow hardness gradient | ACUSHNET COMPANY (US) | 2015-06-16 | — | — | US | disclosed |
| US-8968117-B2 | Dual-core comprising zero gradient center and positive gradient outer core layer | ACUSHNET COMPANY (US) | 2015-03-03 | — | — | US | disclosed |
| CN-103877703-A | Dual-Core Comprising Zero Gradient Center And Positive Gradient Outer Core Layer | ACUSHNET CO | 2014-06-25 | — | — | CN | disclosed |
| US-20130109506-A1 | GOLF BALL COMPRISING A CORE HAVING A SHALLOW HARDNESS GRADIENT | ACUSHNET COMPANY (US) | 2013-05-02 | — | — | US | disclosed |
| US-20130109504-A1 | DUAL-CORE COMPRISING ZERO GRADIENT CENTER AND POSITIVE GRADIENT OUTER CORE LAYER | ACUSHNET COMPANY (US) | 2013-05-02 | — | — | US | disclosed |
| US-7786314-B2 | Processes for preparing bicyclo [3.1.0] hexane derivatives, and intermediates thereto | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2010-08-31 | — | — | US | disclosed |
| US-20070112030-A1 | Processes for preparing bicyclo [3.1.0] hexane derivatives, and intermediates thereto | MERCK & CO., INC. | 2007-05-17 | — | — | US | disclosed |
| US-6967229-B2 | Carbon-carbon initiators for use in golf balls | ACUSHNET COMPANY (US) | 2005-11-22 | — | — | US | disclosed |
| US-20050009992-A1 | Carbon-carbon initiators for use in golf balls | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112030-A1 | Processes for preparing bicyclo [3.1.0] hexane derivatives, and intermediates thereto | GRM1, GRM3, GRM2 | THRB 2401/4885DPP4 2743/4885F2 3499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.