Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 1/20 | 0.57 |
| ▸ | SCN1A | P35498 | 1/20 | 0.57 |
| ▸ | SCN4A | P35499 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.57 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.57 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.57 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.57 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | TNKS | O95271 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4384456 | 0.98 | ALDH1A1 (0.59) | ALDH1A1CYP2C9CACNA1FMAPTHTR2A | |
| SCHEMBL4384462 | 0.98 | ALDH1A1 (0.59) | ALDH1A1CYP2C9CACNA1FMAPTHTR2A | |
| SCHEMBL542865 | 0.98 | ALDH1A1 (0.59) | ALDH1A1CYP2C9CACNA1FMAPTHTR2A | |
| SCHEMBL542225 | 0.87 | TNKS (0.62) | ALDH1A1CYP2C9CACNA1FMAPTHTR2A | |
| SCHEMBL542561 | 0.80 | LMNA (0.53) | ALDH1A1CYP2C9CACNA1FMAPTHTR2A | |
| SCHEMBL1092035 | 0.80 | MEN1 (0.49) | ALDH1A1CYP2C9CACNA1FMAPTHTR2A | |
| SCHEMBL20134878 | 0.80 | LMNA (0.53) | ALDH1A1CYP2C9CACNA1FMAPTHTR2A | |
| SCHEMBL4380000 | 0.80 | MEN1 (0.49) | ALDH1A1CYP2C9CACNA1FMAPTHTR2A | |
| SCHEMBL4380003 | 0.80 | MEN1 (0.49) | ALDH1A1CYP2C9CACNA1FMAPTHTR2A | |
| SCHEMBL17570773 | 0.78 | LMNA (0.51) | MMP2MMP9TNKSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6919365-B2 | Imidazolidinedione derivatives and use thereof as drugs | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2005-07-19 | — | — | US | disclosed |
| US-20040110811-A1 | Novel imidazolidinedione derivatives and use thereof as drugs | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2004-06-10 | — | — | US | disclosed |
| EP-1384715-A1 | NOVEL IMIDAZOLIDINEDIONE DERIVATIVES AND USE THEREOF AS DRUGS | Senju Pharmaceutical Co., Ltd. (JP) | 2004-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110811-A1 | Novel imidazolidinedione derivatives and use thereof as drugs | CMA1, TPSD1, TPSB2 | ALDH1A1 270/4885CYP2C9 121/4885CACNA1F 1795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.