⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30994515 | 0.74 | KDM4E (0.50) | — | |
| SCHEMBL1062978 | 0.73 | CYP11B1 (0.47) | — | |
| SCHEMBL21661952 | 0.73 | KDM1A (0.51) | — | |
| SCHEMBL4390590 | 0.70 | CCR1 (0.46) | — | |
| SCHEMBL15097694 | 0.67 | LDHA (0.52) | — | |
| SCHEMBL4385503 | 0.66 | KDM4E (0.61) | — | |
| SCHEMBL4821580 | 0.65 | — | — | |
| SCHEMBL21241351 | 0.62 | MTNR1A (0.32) | — | |
| SCHEMBL28012680 | 0.62 | CASP3 (0.48) | — | |
| SCHEMBL14273549 | 0.62 | NPC1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567527-A1 | CONDENSED PYRAZOLO DERIVATIVES | ELI LILLY AND COMPANY (US) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004050659-A1 | NOVEL COMPOUNDS AS PHARMACEUTICAL AGENTS | ELI LILLY AND COMPANY (US) | 2004-06-17 | — | — | WO | disclosed |