Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421901 | 0.78 | TSHR (0.52) | MAPTSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL12862758 | 0.75 | TSHR (0.43) | MAPTSMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL6276852 | 0.74 | MAPT (0.40) | MAPTNPC1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL5713032 | 0.73 | SMN1; SMN2 (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4442846 | 0.70 | KMT2A (0.60) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6279980 | 0.70 | ADRB2 (0.30) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6284321 | 0.70 | — | — | |
| SCHEMBL18096180 | 0.69 | RECQL (0.43) | MAPTNPC1RAB9AHDAC3HDAC1 | |
| SCHEMBL18650047 | 0.68 | ALDH1A1 (0.53) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12376667 | 0.68 | MAPT (0.55) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6841703-B2 | Open chain alkoxyamine compounds and their use as polymerization regulators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-01-11 | — | — | US | disclosed |
| EP-1100772-B1 | OPEN CHAIN ALKOXYAMINE COMPOUNDS AND THEIR USE AS POLYMERIZATION REGULATORS | CIBA SC HOLDING AG (CH) | 2004-04-14 | — | — | EP | disclosed |
| US-20030125489-A1 | Open chain alkoxyamine compounds and their use as polymerization regulators | NESVADBA PETER (CH) | 2003-07-03 | — | — | US | disclosed |
| US-6518326-B1 | Open chain alkoxyamine compounds and their use as polymerization regulators | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125489-A1 | Open chain alkoxyamine compounds and their use as polymerization regulators | ALOX5, PTGER1, ALOX12 | MAPT 3566/4885NPC1 3043/4885RAB9A 4808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.